Evidence map›Paper›PMID 18174828›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2008

Predictors of stability of attention-deficit/hyperactivity disorder subtypes from childhood to young adulthood.

Richard D Todd, Hongyan Huang, Alexandre A Todorov, Rosalind J Neuman, Angela M Reiersen, Cynthia A Henderson, Wendy C Reich

Abstract readTwin Study
PubMed Publisher
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. The prevalence of DSM-IV attention-deficit/hyperactivity disorder: a meta-analytic review.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2012
    Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Toward a Revised Nosology for Attention-Deficit/Hyperactivity Disorder Heterogeneity.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2020
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Richard D ToddDrs. Todd, Huang, Todorov, Neuman, Reiersen, Henderson, and Reich are with the Department of Psychiatry, Washington University School of Medicine; Dr. Todd is also with the Department of Genetics. Electronic address: toddr@wustl.edu.
Hongyan HuangDrs. Todd, Huang, Todorov, Neuman, Reiersen, Henderson, and Reich are with the Department of Psychiatry, Washington University School of Medicine; Dr. Todd is also with the Department of Genetics.
Alexandre A TodorovDrs. Todd, Huang, Todorov, Neuman, Reiersen, Henderson, and Reich are with the Department of Psychiatry, Washington University School of Medicine; Dr. Todd is also with the Department of Genetics.
Rosalind J NeumanDrs. Todd, Huang, Todorov, Neuman, Reiersen, Henderson, and Reich are with the Department of Psychiatry, Washington University School of Medicine; Dr. Todd is also with the Department of Genetics.
Angela M ReiersenDrs. Todd, Huang, Todorov, Neuman, Reiersen, Henderson, and Reich are with the Department of Psychiatry, Washington University School of Medicine; Dr. Todd is also with the Department of Genetics.
Cynthia A HendersonDrs. Todd, Huang, Todorov, Neuman, Reiersen, Henderson, and Reich are with the Department of Psychiatry, Washington University School of Medicine; Dr. Todd is also with the Department of Genetics.
Wendy C ReichDrs. Todd, Huang, Todorov, Neuman, Reiersen, Henderson, and Reich are with the Department of Psychiatry, Washington University School of Medicine; Dr. Todd is also with the Department of Genetics.

Funding

GENETIC EPIDEMIOLOGY OF ADHDR01MH052813 · NIMH · WASHINGTON UNIVERSITY · PI TODD, RICHARD D · 1996 to 2005
$3.1M
NIMH NIH HHS R01 MH052813NIMH NIH HHS R01-MH52813
6 · The paper itself

Abstract

objectiveTo determine the 5-year prospective stability of population-based and DSM-IV subtypes of attention-deficit/hyperactivity disorder (ADHD) as well as to explore predictors of stability.

methodA total of 708 twins ages 7 to 19 years who were identified from birth records of the state of Missouri and had participated in a study of ADHD were reassessed 5 years later in a blinded fashion. Stabilities of DSM-IV and population-based ADHD subtypes were compared using percentage of agreement with significance tested by the kappa statistic. Predictors of stability of subtype diagnosis were determined using multivariate logistic regression.

resultsIn general, 5-year ADHD subtype stability was poor to modest and ranged from 11.1% to 24.0% for DSM-IV for subtypes and from 14.3% to 35.3% for clinically significant population-derived subtypes. There were no predictors of diagnostic stability that applied across subtypes. There were subtype-specific predictors including a diagnosis of oppositional defiant disorder for DSM-IV primarily inattentive ADHD; lower verbal IQ for DSM-IV combined type ADHD; and younger age, oppositional defiant disorder, and medication use for population-defined severe combined ADHD.

conclusionsPopulation-defined ADHD subtype criteria demonstrated modestly improved diagnostic stability over 5 years compared to DSM-IV subtypes. Few correlates or predictors of stability were identified.

Indexed as

AdolescentAdultAttention Deficit and Disruptive Behavior DisordersAttention Deficit Disorder with HyperactivityChildComorbidityDiagnostic and Statistical Manual of Mental DisordersDiseases in TwinsFemaleGenetic Predisposition to DiseaseHumansMalePhenotypePrognosisProspective Studies

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.