ArticleJournal of clinical microbiology2008
Diarrheagenic Escherichia coli and Shigella strains isolated from children in a hospital case-control study in Hanoi, Vietnam.
Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.
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Who cites it
40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- Childhood diarrhoea attributed to enteropathogenic bacteria in low- and middle-income countries: a systematic review and meta-analysis.Journal of global health · 2025Pooled it
- Enteroaggregative Escherichia coli and acute diarrhea in children: a meta-analysis of South Asian populations.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2013Pooled it
- Review
- Lactose fermenting enteroinvasive Escherichia coli from diarrhoeal cases confers enhanced virulence.Scientific reports · 2025Article
- Incidence rates of resistant enterotoxigenic Escherichia coli in fresh vegetables and salads.Access microbiology · 2025Article
- High prevalence of enterotoxigenicFrontiers in microbiology · 2025Article
- Sequence-subtype association of multi-drug-resistant diarrheagenicIranian journal of microbiology · 2024Article
- Genomic characterization of endemic diarrheagenic Escherichia coli and Escherichia albertii from infants with diarrhea in Vietnam.PLoS neglected tropical diseases · 2023Article
- Diarrhoeal pathogens in the stools of children living with HIV in Ibadan, Nigeria.Frontiers in cellular and infection microbiology · 2023Article
- A systematic review and meta-analysis of integrated studies on antimicrobial resistance in Vietnam, with a focus onOne health (Amsterdam, Netherlands) · 2022Review
- Field evaluation of a novel, rapid diagnostic assay, and molecular epidemiology of enterotoxigenic E. coli among Zambian children presenting with diarrhea.PLoS neglected tropical diseases · 2022Article
- Incidence of AsymptomaticLife (Basel, Switzerland) · 2022Article
- Risk Factors Associated with Diarrheal Episodes in an Agricultural Community in Nam Dinh Province, Vietnam: A Prospective Cohort Study.International journal of environmental research and public health · 2022Article
- DETECTION OF DIARRHEAGENICAfrican journal of infectious diseases · 2021Article
- Molecular and genome characterization of colistin-resistant Escherichia coli isolates from wild sea lions (Zalophus californianus).Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020Article
- Novel multiplex real-time PCR assays reveal a high prevalence of diarrhoeagenic Escherichia coli pathotypes in healthy and diarrhoeal children in the south of Vietnam.BMC microbiology · 2020Article
- Distribution of Genes Encoding Virulence Factors and the Genetic Diversity of EnteroinvasiveInfection and drug resistance · 2020Article
- Detection and Characterization of Enteropathogenic and Shiga Toxin-ProducingFrontiers in microbiology · 2018Article
- Antibiotic resistance pattern and molecular characterization of extended-spectrum β-lactamase producing enteroaggregativeInfection and drug resistance · 2018Article
- Seasonal and geographical distribution of bacillary dysentery (shigellosis) and associated climate risk factors in Kon Tam Province in Vietnam from 1999 to 2013.Infectious diseases of poverty · 2017Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This case-control study detected and characterized Shigella and diarrheagenic Escherichia coli (DEC) types among Vietnamese children less than 5 years old. In 249 children with diarrhea and 124 controls, Shigella spp. was an important cause of diarrhea (P < 0.05). We used multiplex PCR and DNA probes to detect enteroinvasive E. coli (EIEC), enteroaggregative E. coli (EAggEC), enteropathogenic E. coli (EPEC), attaching and effacing E. coli (A/EEC), verocytotoxin-producing E. coli (VTEC), and enterotoxigenic E. coli (ETEC). The prevalences of DEC in the diarrhea and control groups were 25.7 and 10.5%, respectively. In 62 children with diarrhea, 64 DEC strains included 22 EAggEC (8.8%), 2 EIEC (0.8%), 23 A/EEC (9.2%), 7 EPEC (2.8%), and 10 ETEC strains (4.0%). Among controls, 13 DEC strains included 5 EAggEC strains (4.0%), 7 A/EEC strains (5.6%), and 1 EPEC strain. The characterization of DEC by serotypes, antimicrobial susceptibility patterns, virulence genes, and pulsed-field gel electrophoresis showed the occurrence of many different and highly heterogenic DEC subtypes, but common serotypes were found among ETEC, EIEC and EPEC, respectively. Serotyping was used to distinguish between A/EEC and EPEC. However, A/EEC, EPEC, and EAggEC were isolated at high frequency from both cases and controls. Further in-depth studies are needed to better understand important virulence factors of DEC, especially A/EEC, EPEC, and EAggEC.
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