ReviewAnnual review of immunology2008
Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organs.
Review in Annual review of immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 161 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
161 citing papers in PubMed, 300 citations in OpenAlex.
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- Light-inducible T cell engagers trigger, tune, and shape the activation of primary T cells.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Random walk informed heterogeneity detection reveals how the lymph node conduit network influences T cells collective exploration behavior.PLoS computational biology · 2023Article
- Non-radioactive imaging strategies forPhysical sciences reviews · 2023Article
- Two-photon excitation fluorescence in ophthalmology: safety and improved imaging for functional diagnostics.Frontiers in medicine · 2023Review
- Immune dynamics in the CNS and its barriers during homeostasis and disease.Immunological reviews · 2022Review
- De-risking clinical trial failure through mechanistic simulation.Immunotherapy advances · 2022Article
- Mechanotransduction as a major driver of cell behaviour: mechanisms, and relevance to cell organization and future research.Open biology · 2021Review
- Transduction catalysis: Doxorubicin amplifies rAAV-mediated gene expression in the cortex of higher-order vertebrates.iScience · 2021Article
- Characterization of immune cell migration using microfabrication.Biophysical reviews · 2021Review
- Article
- Labeling and tracking of immune cells in ex vivo human skin.Nature protocols · 2021Article
- Spatially resolved measurement of dynamic glucose uptake in live ex vivo tissues.Analytica chimica acta · 2021Article
- Intravital imaging of interactions between iNKT and kupffer cells to clear free lipids during steatohepatitis.Theranostics · 2021Article
- Review
101 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The immune system is the most diffuse cellular system in the body. Accordingly, long-range migration of cells and short-range communication by local chemical signaling and by cell-cell contacts are vital to the control of an immune response. Cellular homing and migration within lymphoid organs, antigen recognition, and cell signaling and activation are clearly vital during an immune response, but these events had not been directly observed in vivo until recently. Introduced to the field of immunology in 2002, two-photon microscopy is the method of choice for visualizing living cells deep within native tissue environments, and it is now revealing an elegant cellular choreography that underlies the adaptive immune response to antigen challenge. We review cellular dynamics and molecular factors that contribute to basal motility of lymphocytes in the lymph node and cellular interactions leading to antigen capture and recognition, T cell activation, B cell activation, cytolytic effector function, and antibody production.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.