Evidence map›Paper›PMID 18172715›Full record

ArticleCurrent microbiology2008

Purification and partial characterization of novel bacteriocin L23 produced by Lactobacillus fermentum L23.

Liliana M Pascual, María B Daniele, Walter Giordano, María C Pájaro, Isabel L Barberis

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
7.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 97 citations in OpenAlex.

  1. Review
  2. Article
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  13. Probiotics or pro-healers: the role of beneficial bacteria in tissue repair.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2017
    Review
  14. Article
  15. TwoFrontiers in microbiology · 2017
    Article
  16. Antimicrobial Compounds Produced by VaginalFrontiers in microbiology · 2017
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  17. Review
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Liliana M PascualDepartamento de Microbiología e Inmunología, Universidad Nacional de Río Cuarto, 5800, Río Cuarto, Córdoba, Argentina.
María B Daniele
Walter Giordano
María C Pájaro
Isabel L Barberis
National University of Río Cuarto · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactobacillus fermentum strain L23 produced a small bacteriocin, designated bacteriocin L23, with an estimated molecular mass of < 7000 Da. Isolation, purification, and partial characterization of bacteriocin L23 are described. It displayed a wide inhibitory spectrum including both Gram-negative and Gram-positive pathogenic strains and two species of Candida. The antibacterial activity of cell-free culture supernatant fluid was not affected by catalase or urease but was abolished by the proteolytic enzymes trypsin and protease VI. Bacteriocin L23 was heat stable (60 min at 100 degrees C) and showed inhibitory activity over a wide pH range (4.0 to 7.0). The proteinaceous compound was isolated from cell-free culture supernatant fluid and purified. Crude bacteriocin sample was prepared by a process of ammonium sulfate precipitation, gel filtration, thin-layer chromatography, bioautography, and reversed-phase HPLC.

Indexed as

Ammonium SulfateAnti-Bacterial AgentsBacterial ProteinsBacteriocinsCandidaChemical FractionationChromatography, GelChromatography, High Pressure LiquidChromatography, Thin LayerFemaleGram-Negative BacteriaGram-Positive BacteriaHot TemperatureHumansHydrogen-Ion ConcentrationLimosilactobacillus fermentumAmmonium SulfateAnti-Bacterial AgentsBacterial ProteinsBacteriocinsTrypsin

Identifiers

PMID18172715
OpenAlexW2034564401

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.