ArticleAdvances in enzyme regulation2008
Protein kinase C isozymes as therapeutic targets for treatment of human cancers.
Article in Advances in enzyme regulation, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Trial
- PRKCI-ECT2 copy number gain promotes developmental reprogramming and metastatic competence in lung adenocarcinoma.Cell reports · 2026Article
- Protein Kinase C Family: Structures, Biological Functions, Diseases, and Pharmaceutical Interventions.MedComm · 2025Review
- Structure-activity relationship of a peptide permeation enhancer.Tissue barriers · 2023Article
- Impact of peptide permeation enhancer on tight junctions opening cellular mechanisms.Biochemistry and biophysics reports · 2022Article
- Article
- Clinical significance of atypical protein kinase C (PKCι and PKCζ) and its relationship with yes-associated protein in lung adenocarcinoma.BMC cancer · 2019Article
- The roles of PKCs in regulating autophagy.Journal of cancer research and clinical oncology · 2018Review
- Downregulation of PKCζ/Pard3/Pard6b is responsible for lung adenocarcinoma cell EMT and invasion.Cellular signalling · 2017Article
- Inhibition of PKCα reduces the ability of migration of kidney cancer cells but has no impact on cell apoptosis.Experimental and therapeutic medicine · 2017Article
- Article
- The chromosome 3q26 OncCassette: A multigenic driver of human cancer.Advances in biological regulation · 2016Article
- Protein kinase Cδ promotes proliferation and induces malignant transformation in skeletal muscle.Journal of cellular and molecular medicine · 2015Article
- Protein kinase Cα suppresses Kras-mediated lung tumor formation through activation of a p38 MAPK-TGFβ signaling axis.Oncogene · 2014Article
- Knockout mouse models of insulin signaling: Relevance past and future.World journal of diabetes · 2014Review
- Atypical protein kinase Cι as a human oncogene and therapeutic target.Biochemical pharmacology · 2014Review
- Article
- Protein kinase C zeta regulates human pancreatic cancer cell transformed growth and invasion through a STAT3-dependent mechanism.PloS one · 2013Article
- Protein kinase Cα promotes cell migration through a PDZ-dependent interaction with its novel substrate discs large homolog 1 (DLG1).The Journal of biological chemistry · 2011Article
- Basic aspects of tumor cell fatty acid-regulated signaling and transcription factors.Cancer metastasis reviews · 2011Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.