ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2008
Blood conservation strategies to reduce the need for red blood cell transfusion in critically ill patients.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Interventions to prevent iatrogenic anemia: a Laboratory Medicine Best Practices systematic review.Critical care (London, England) · 2019Pooled it
- Recommendations for the transfusion management of patients in the peri-operative period. I. The pre-operative period.Blood transfusion = Trasfusione del sangue · 2011Guideline
- Anemia and red blood cell transfusion in neurocritical care.Critical care (London, England) · 2009Pooled it
- Determination of the Minimum Discard Volume in the Extraction of Blood Samples Through Arterial Catheters in Critical Patients.Nursing in critical care · 2026Article
- Perioperative management of acetabular and pelvic fractures: evidence-based recommendations.Archives of orthopaedic and trauma surgery · 2023Review
- Risk Factors Analysis for Hemoglobin Decline Caused by Diagnostic Blood Collection in Respiratory Department in North China: A Case-Control Study.International journal of general medicine · 2023Article
- Cell Salvage at the ICU.Journal of clinical medicine · 2022Review
- Liberal Transfusion versus Restrictive Transfusion and Outcomes in Critically Ill Adults: A Meta-Analysis.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2021Review
- Blood Transfusion for Elderly Patients with Hip Fracture: a Nationwide Cohort Study.Journal of Korean medical science · 2020Article
- Blood conservation devices in critical care: a narrative review.Annals of intensive care · 2013Review
- Critical evaluation of justifications for the transfusion of red blood cells: the reality of a government emergency hospital.Revista brasileira de hematologia e hemoterapia · 2013Article
- Transfusion and risk of infection in Canada: Update 2012.Paediatrics & child health · 2012Article
- Anemia and blood transfusions in critically ill patients.Journal of blood transfusion · 2012Review
- Red blood cell transfusion in the critically ill patient.Annals of intensive care · 2011Article
- Mortality following blood transfusion for non-variceal upper gastrointestinal bleeding.Frontline gastroenterology · 2011Article
- Classifying transfusions related to the anemia of critical illness in burn patients.The Journal of trauma · 2011Article
- The use of a blood conservation device to reduce red blood cell transfusion requirements: a before and after study.Critical care (London, England) · 2010Article
- [Anemia and transfusion therapy: an update].Medicina intensivaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anemia commonly affects critically ill patients. The causes are multifactorial and include acute blood loss, blood loss from diagnostic testing and blunted red blood cell production. Blood transfusions are frequently given to patients in intensive care units to treat low hemoglobin levels due to either acute blood loss or subacute anemia associated with critical illness. Although blood transfusion is a life-saving therapy, evidence suggests that it may be associated with an increased risk of morbidity and mortality. A number of blood conservation strategies exist that may mitigate anemia in hospital patients and limit the need for transfusion. These strategies include the use of hemostatic agents, hemoglobin substitutes and blood salvage techniques, the reduction of blood loss associated with diagnostic testing, the use of erythropoietin and the use of restrictive blood transfusion triggers. Strategies to reduce blood loss associated with diagnostic testing and the use of hemostatic agents and erythropoietin result in higher hemoglobin levels, but they have not been shown to reduce the need for blood transfusions or to improve clinical outcomes. Lowering the hemoglobin threshold at which blood is transfused will reduce the need for transfusions and is not associated with increased morbidity or mortality among most critically ill patients without active cardiac disease. Further research is needed to determine the potential roles for other blood conservation strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.