Evidence map›Paper›PMID 18165353›Full record

ArticleDiabetes2008

An apparent role for Alox15 in the pathogenesis of diabetes in the NOD mouse: parsing the supporting genetic data.

Stuart P Weisberg, Rudolph L Leibel

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Diabetes, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Nonviral delivery of small interfering RNA into pancreas-associated immune cells prevents autoimmune diabetes.Molecular therapy : the journal of the American Society of Gene Therapy · 2012
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Stuart P WeisbergDivision of Molecular Genetics, Naomi Berrie Diabetes Center, Columbia University, New York, New York 10032, USA. spw13@columbia.edu
Rudolph L Leibel
Columbia University · US

Funding

The molecular genetic analysis of human obesityR01DK052431 · NIDDK · ROCKEFELLER UNIVERSITY · PI CHUNG, WENDY K, LEIBEL, RUDOLPH L · 1996 to 2020
$11.6M
Cloning of a type 2 diabetes modifier in obese miceR01DK066518 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LEIBEL, RUDOLPH L · 2003 to 2011
$4.2M
NIDDK NIH HHS R01 DK052431NIDDK NIH HHS R01 DK066518
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsArachidonate 12-LipoxygenaseArachidonate 15-LipoxygenaseDiabetes Mellitus, Type 1Disease Models, AnimalHumansInsulin-Secreting CellsMiceMice, Inbred NODMultienzyme ComplexesAlox15 protein, mouseArachidonate 12-LipoxygenaseArachidonate 15-LipoxygenaseMultienzyme Complexes

Identifiers

PMID18165353
OpenAlexW2170550355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.