ReviewNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2008
The treatment of movement disorders by deep brain stimulation.
Review in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06585618 (Multicenter Pediatric Deep Brain Stimulation Registry), which is not on this map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Multicenter Pediatric Deep Brain Stimulation Registry
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 103 citations in OpenAlex.
- Deep brain stimulation in PD: risk of complications, morbidity, and hospitalizations: a systematic review.Frontiers in aging neuroscience · 2023Pooled it
- Pooled it
- Feasibility of Real-Time Autonomous Functional Electrical Stimulation for Freezing of Gait.The European journal of neuroscience · 2026Article
- Deep brain stimulation for chronic pain: mechanisms, clinical applications, limitations, and future directions.Frontiers in medicine · 2025Review
- Deep brain stimulation in a pediatric dystonia patient with cochlear implants and mitochondrial disorder: novel application of a frameless stereotactic system and navigating the anesthesia choice and neurosurgical complexities. Illustrative case.Journal of neurosurgery. Case lessons · 2023Article
- Increasing the transmission efficiency of transcranial ultrasound using a dual-mode conversion technique based on Lamb waves.The Journal of the Acoustical Society of America · 2022Article
- Neurotechnological Approaches to the Diagnosis and Treatment of Alzheimer's Disease.Frontiers in neuroscience · 2022Review
- The Child & Youth CompreHensIve Longitudinal Database for Deep Brain Stimulation (CHILD-DBS).Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- Directions of Deep Brain Stimulation for Epilepsy and Parkinson's Disease.Frontiers in neuroscience · 2021Review
- A Novel Intervention Technology for Cerebral Palsy: Brain Stimulation.Iranian journal of child neurology · 2019Review
- Magnetic Resonance-Guided Focused Ultrasound : Current Status and Future Perspectives in Thermal Ablation and Blood-Brain Barrier Opening.Journal of Korean Neurosurgical Society · 2019Article
- Deep brain stimulation in a rat model of post-traumatic stress disorder modifies forebrain neuronal activity and serum corticosterone.Iranian journal of basic medical sciences · 2018Article
- MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor.Journal of visualized experiments : JoVE · 2017Article
- Current and emerging brain applications of MR-guided focused ultrasound.Journal of therapeutic ultrasound · 2017Review
- An Overview of Translationally Informed Treatments for Posttraumatic Stress Disorder: Animal Models of Pavlovian Fear Conditioning to Human Clinical Trials.Biological psychiatry · 2015Review
- Technology for deep brain stimulation at a gallop.Movement disorders : official journal of the Movement Disorder Society · 2015Review
- Two-year outcomes of deep brain stimulation in adults with cerebral palsy.Annals of rehabilitation medicine · 2014Article
- Clinical applications involving CNS gene transfer.Advances in genetics · 2014Review
- Engineering animal models of dystonia.Movement disorders : official journal of the Movement Disorder Society · 2013Review
- Chronic high-frequency stimulation therapy in hemiparkinsonian rhesus monkeys using an implanted human DBS system.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been understood, for some time, that modulation of deep brain nuclei within the basal ganglia and thalamus can have a therapeutic effect in patients with movement disorders. Because of its reversibility and adjustability, deep brain stimulation (DBS) has largely come to replace traditional ablation procedures. The clinical effects of DBS vary, depending both on the target being stimulated and on the parameters of stimulation. Both aspects are currently the subject of substantial research and discovery. The most common targets for DBS treatment include the subthalamic nucleus for the treatment of advanced Parkinson's disease, the ventral intermediate nucleus of the thalamus for the treatment of medically refractory essential tremor, and the globus pallidus interna for the treatment of both cervical and generalized dystonias and Parkinson's disease. We review the current indications, targets, outcomes, and general procedure of DBS for essential tremor, Parkinson's disease, and dystonia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.