Evidence map›Paper›PMID 18163952›Full record

ReviewCellular & molecular immunology2007

The interferon signaling network and transcription factor C/EBP-beta.

Hui Li, Padmaja Gade, Weihua Xiao, Dhan V Kalvakolanu

Abstract readReview
In one paragraph

Review in Cellular & molecular immunology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Intestinal epithelialActa biochimica et biophysica Sinica · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Role of STAT1 in the resistance of HBV to IFN-α.Experimental and therapeutic medicine · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hui LiDepartment of Microbiology & Immunology, Greenebaum Cancer Center, University of Maryland School of Medicine, 660 W. Redwood Street, Baltimore, MD 21201, USA.
Padmaja Gade
Weihua Xiao
Dhan V Kalvakolanu

Funding

MODULATION OF IFN ACTION VIA NOVEL REGULATORY FACTORSR01CA078282 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI KALVAKOLANU, DHAN V. · 1998 to 2014
$4.4M
Cytokine modulated novel growth inhibitory mechanismsR01CA105005 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI KALVAKOLANU, DHAN V. · 2004 to 2013
$2.7M
NCI NIH HHS CA78282NCI NIH HHS R01 CA078282NCI NIH HHS R01 CA105005
6 · The paper itself

Abstract

Cytokines like interferons (IFNs) play a central role in regulating innate and specific immunities against the pathogens and neoplastic cells. A number of signaling pathways are induced in response to IFN in various cells. One classic mechanism employed by IFNs is the JAK-STAT signaling pathway for inducing cellular responses. Here we describe the non-STAT pathways that participate in IFN-induced responses. In particular, we will focus on the role played by transcription factor C/EBP-beta in mediating these responses.

Indexed as

CCAAT-Enhancer-Binding Protein-betaInterferonsAnimalsHumansImmunity, InnateImmunotherapyIntercellular Signaling Peptides and ProteinsIntracellular Signaling Peptides and ProteinsJanus KinasesMAP Kinase Signaling SystemParacrine CommunicationSignal TransductionSTAT Transcription FactorsCCAAT-Enhancer-Binding Protein-betaIntercellular Signaling Peptides and ProteinsInterferonsIntracellular Signaling Peptides and ProteinsJanus KinasesSTAT Transcription Factors

Identifiers

PMID18163952
PMCPMC2782719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.