ArticleSleep & breathing = Schlaf & Atmung2008
Cheyne stokes breathing at high altitude: a helpful response or a troublemaker?
Article in Sleep & breathing = Schlaf & Atmung, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- The effect of acetazolamide on sleep apnea at high altitude: a systematic review and meta-analysis.Therapeutic advances in respiratory disease · 2017Pooled it
- Periodic breathing in healthy young adults in normobaric hypoxia equivalent to 3500 m, 4500 m, and 5500 m altitude.Sleep & breathing = Schlaf & Atmung · 2019Trial
- Prediction of acute mountain sickness occurring at 4554 m using overnight pulse oximetry from lower altitude: A pilot study.Experimental physiology · 2026Article
- AdaptiveiScience · 2025Article
- Brazilian Thoracic Association Consensus on Sleep-disordered Breathing.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022Article
- Relationship between cardiorespiratory phase coherence during hypoxia and genetic polymorphism in humans.The Journal of physiology · 2020Article
- Relationships Between Chemoreflex Responses, Sleep Quality, and Hematocrit in Andean Men and Women.Frontiers in physiology · 2020Article
- The correct measurement of oxygen saturation at high altitude.Sleep & breathing = Schlaf & Atmung · 2019Article
- Normobaric hypoxia overnight impairs cognitive reaction time.BMC neuroscience · 2017Article
- 2015 ATS conference sleep talks overshadowed by the discussion about ASV negative outcome in heart failure: sleep medicine highlights from the 2015 ATS annual conference in Denver.Sleep & breathing = Schlaf & Atmung · 2015Article
- Neurology and altitude illness.Neurology. Clinical practice · 2015Article
- The impact of altitude on the sleep of young elite soccer players (ISA3600).British journal of sports medicine · 2013Article
- The effects of altitude associated central apnea on the diagnosis and treatment of obstructive sleep apnea: comparative data from three different altitude locations in the mountain west.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2011Article
- Do over 200 million healthy altitude residents really suffer from chronic Acid-base disorders?Indian journal of clinical biochemistry : IJCB · 2011Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sleep disorders at high altitude are common and well-known for centuries. One symptom of the complex is periodic breathing (PB). PB occurs from a disbalance of the negative feedback loop of ventilation control, and at high altitude, it is increased by a phase shift of 180 degrees between hyperventilation and hypoxia. This paper explains the mechanisms that trigger the problem and discusses whether PB may be of advantage or disadvantage for the person going to high altitude. Up to about 3,000-3,500 m, PB may be of advantage because it stabilizes oxygen saturation at a relatively high level. At higher altitudes, disadvantages predominate because frequent arousals cause total sleep deprivation and mental and physical impairment of the victim. Correct acclimatization and "defensive" altitude profiles are gold standard, which minimize PB and optimizes recreative sleep, although they cannot mask PB completely, especially at extreme altitude.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.