ArticleDigestive diseases and sciences2008
Response to hepatitis B vaccination in patients with celiac disease.
Article in Digestive diseases and sciences, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Immune response to Hepatitis B vaccine in patients with celiac disease: A systematic review and meta-analysis.Human vaccines & immunotherapeutics · 2015Pooled it
- Immune response of hepatitis B vaccine among persons with diabetes: a systematic review of the literature.Diabetes care · 2012Pooled it
- Intramuscular vs intradermal route for hepatitis B booster vaccine in celiac children.World journal of gastroenterology · 2012Trial
- Hepatitis B virus infection after immunization: How serious it is? An updated review.Clinical and experimental medicine · 2025Review
- Viral infections in celiac disease: what should be considered for better management.Clinical and experimental medicine · 2024Review
- Clinical Characteristics of Children With Celiac Disease Not Responding to Hepatitis B Vaccination in India.JPGN reports · 2021Article
- Vaccinations and Immune Response in Celiac Disease.Vaccines · 2020Review
- Co-Administration of Injected and Oral Vaccine Candidates Elicits Improved Immune Responses over Either Route Alone.Vaccines · 2020Article
- Celiac Disease: Extraintestinal Manifestations and Associated Conditions.Journal of clinical gastroenterology · 2020Review
- How the gut microbiome regulates host immune responses to viral vaccines.Current opinion in virology · 2019Review
- Factors That Influence the Immune Response to Vaccination.Clinical microbiology reviews · 2019Review
- Immune response to hepatitis B virus vaccine in celiac subjects at diagnosis.World journal of hepatology · 2016Article
- Influence of the microbiome on response to vaccination.Human vaccines & immunotherapeutics · 2015Article
- Article
- Evaluation of the response to vaccination with hepatitis B vaccine in pediatric patients diagnosed with celiac disease.SAGE open medicine · 2014Article
- Role of gluten intake at the time of hepatitis B virus vaccination in the immune response of celiac patients.Clinical and vaccine immunology : CVI · 2013Article
- Hepatitis B vaccine in celiac disease: yesterday, today and tomorrow.World journal of gastroenterology · 2013Review
- Production of highly concentrated, heat-stable hepatitis B surface antigen in maize.Plant biotechnology journal · 2012Article
- Bioencapsulation of the hepatitis B surface antigen and its use as an effective oral immunogen.Vaccine · 2012Article
- New hepatitis B vaccine schedule for children with celiac disease.Hepatitis monthly · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Abnormal immune response to gliadin, genetic, and environmental factors play a role in the pathogenesis of celiac disease (CD). Non-responsiveness to hepatitis B virus (HBV) vaccination is related to genetic features. Certain human leukocyte antigen (HLA) genotypes are more prevalent among non-responders to HBV vaccination. There is also a strong relationship between CD and these HLA genotypes. This study investigates the relationship between CD and non-responsiveness to HBV vaccination, with an emphasis on genotypic co-incidence. No statistically significant difference was noted between the ages and gender of CD patients and control subjects. Baseline serum IgA, IgM, and IgG levels of all CD patients were normal. Responsiveness to HBV vaccination was observed in 17 (68%) CD patients and all (100%) control subjects (P = 0.006). In conclusion, CD should also be sought in unresponders to HBV vaccine who are not immunosuppressed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.