ReviewPflugers Archiv : European journal of physiology2008
High-speed AFM and nano-visualization of biomolecular processes.
Review in Pflugers Archiv : European journal of physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed.
- Imaging Artificial Membranes Using High-Speed Atomic Force Microscopy.Methods in molecular biology (Clifton, N.J.) · 2027Article
- SimHS-AFMfit-MD: An Integrative Approach for Inferring Alpha-Actinin Atomic Conformational Dynamics.Nano letters · 2026Article
- Automatic PID Control Strategy via Energy Dissipation for Tapping Mode Atomic Force Microscopy.Sensors (Basel, Switzerland) · 2025Article
- AFM observation of protein translocation mediated by one unit of SecYEG-SecA complex.Nature communications · 2025Article
- Single-Molecule Kinetic Observation of Antibody Interactions with Growing Amyloid β Fibrils.Journal of the American Chemical Society · 2024Article
- Article
- Observing Dynamic Conformational Changes within the Coiled-Coil Domain of Different Laminin Isoforms Using High-Speed Atomic Force Microscopy.International journal of molecular sciences · 2024Article
- Molecular Design of FRET Probes Based on Domain Rearrangement of Protein Disulfide Isomerase for Monitoring Intracellular Redox Status.International journal of molecular sciences · 2023Article
- Few-shot deep learning for AFM force curve characterization of single-molecule interactions.Patterns (New York, N.Y.) · 2023Article
- Removing the parachuting artifact using two-way scanning data in high-speed atomic force microscopy.Biophysics and physicobiology · 2023Article
- Diffracted X-ray Tracking Method for Measuring Intramolecular Dynamics of Membrane Proteins.International journal of molecular sciences · 2022Review
- Article
- Dynamic Assembly/Disassembly ofInternational journal of molecular sciences · 2021Article
- Biological physics by high-speed atomic force microscopy.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2020Review
- Resolving the data asynchronicity in high-speed atomic force microscopy measurement via the Kalman Smoother.Scientific reports · 2020Article
- Microscopic Techniques for the Analysis of Micro and Nanostructures of Biopolymers and Their Derivatives.Polymers · 2020Review
- Algal Viruses: The (Atomic) Shape of Things to Come.Viruses · 2018Review
- Ultrafast current imaging by Bayesian inversion.Nature communications · 2018Article
- Production of Single-Chain Fv Antibodies Specific for GA-Pyridine, an Advanced Glycation End-Product (AGE), with Reduced Inter-Domain Motion.Molecules (Basel, Switzerland) · 2017Article
- Imaging and Force Recognition of Single Molecular Behaviors Using Atomic Force Microscopy.Sensors (Basel, Switzerland) · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Conventional atomic force microscopes (AFMs) take at least 30-60 s to capture an image, while dynamic biomolecular processes occur on a millisecond timescale or less. To narrow this large difference in timescale, various studies have been carried out in the past decade. These efforts have led to a maximum imaging rate of 30-60 ms/frame for a scan range of approximately 250 nm, with a weak tip-sample interaction force being maintained. Recent imaging studies using high-speed AFM with this capacity have shown that this new microscope can provide straightforward and prompt answers to how and what structural changes progress while individual biomolecules are at work. This article first compares high-speed AFM with its competitor (single-molecule fluorescence microscopy) on various aspects and then describes high-speed AFM instrumentation and imaging studies on biomolecular processes. The article concludes by discussing the future prospects of this cutting-edge microscopy.
Indexed as
Identifiers
18157545What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.