ArticleExtremophiles : life under extreme conditions2008
Effect of growth temperature on ether lipid biochemistry in Archaeoglobus fulgidus.
Article in Extremophiles : life under extreme conditions, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 67 citations in OpenAlex.
- Mechanistic insight into radicalNatural product reports · 2026Review
- Novel Extended Tetraether Lipids Found in a High-COEnvironmental microbiology · 2026Article
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- The Archaeal Cell Cycle.Annual review of cell and developmental biology · 2024Review
- Unraveling the multiplicity of geranylgeranyl reductases in Archaea: potential roles in saturation of terpenoids.Extremophiles : life under extreme conditions · 2024Review
- The catalytic and structural basis of archaeal glycerophospholipid biosynthesis.Extremophiles : life under extreme conditions · 2022Review
- Highlighting the Unique Roles of RadicalJournal of bacteriology · 2022Review
- Identification of a protein responsible for the synthesis of archaeal membrane-spanning GDGT lipids.Nature communications · 2022Article
- The influence of the specific growth rate on the lipid composition of Sulfolobus acidocaldarius.Extremophiles : life under extreme conditions · 2020Article
- Construction of an artificial biosynthetic pathway for hyperextended archaeal membrane lipids in the bacteriumSynthetic biology (Oxford, England) · 2020Article
- Marine Group II Euryarchaeota Contribute to the Archaeal Lipid Pool in Northwestern Pacific Ocean Surface Waters.Frontiers in microbiology · 2020Article
- Fusion of Bipolar Tetraether Lipid Membranes Without Enhanced Leakage of Small Molecules.Scientific reports · 2019Article
- GDGT cyclization proteins identify the dominant archaeal sources of tetraether lipids in the ocean.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Entropic effects enable life at extreme temperatures.Science advances · 2019Article
- Article
- Gene deletions leading to a reduction in the number of cyclopentane rings in Sulfolobus acidocaldarius tetraether lipids.FEMS microbiology letters · 2018Article
- Adaptations of archaeal and bacterial membranes to variations in temperature, pH and pressure.Extremophiles : life under extreme conditions · 2017Review
- Heat Stress Dictates Microbial Lipid Composition along a Thermal Gradient in Marine Sediments.Frontiers in microbiology · 2017Article
- Effects of Lipid Tethering in Extremophile-Inspired Membranes on H(+)/OH(-) Flux at Room Temperature.Biophysical journal · 2016Article
- Discovery and Characterization of Iron Sulfide and Polyphosphate Bodies Coexisting in Archaeoglobus fulgidus Cells.Archaea (Vancouver, B.C.) · 2016Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The archaea are distinguished by their unique isoprenoid ether lipids, which typically consist of the sn-2,3-diphytanylglycerol diether or sn-2,3-dibiphytanyldiglycerol tetraether core modified with a variety of polar headgroups. However, many hyperthermophilic archaea also synthesize tetraether lipids with up to four pentacyclic rings per 40-carbon chain, presumably to improve membrane thermal stability at temperatures up to approximately 110 degrees C. This study aimed to correlate the ratio of tetraether to diether core lipid, as well as the presence of pentacyclic groups in tetraether lipids, with growth temperature for the hyperthermophilic archaeon, Archaeoglobus fulgidus. Analysis of the membrane core lipids of A. fulgidus using APCI-MS analysis revealed that the tetraether-to-diether lipid ratio increases from 0.3 +/- 0.1 for cultures grown at 70 degrees C to 0.9 +/- 0.1 for cultures grown at 89 degrees C. Thin-layer chromatography (TLC) followed by APCI-MS analysis provided evidence for no more than one pentacycle in the hydrocarbon chains of tetraether lipid from cultures grown at 70 degrees C and up to 2 pentacycles in the tetraether lipid from cultures grown at higher temperatures. Analysis of the polar lipid extract using TLC and negative-ion ESI-MS suggested the presence of diether and tetraether phospholipids with inositol, glycosyl, and ethanolamine headgroup chemistry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.