Evidence map›Paper›PMID 18156262›Full record

ArticleJournal of bacteriology2008

The AraC-like transcriptional regulator DhbR is required for maximum expression of the 2,3-dihydroxybenzoic acid biosynthesis genes in Brucella abortus 2308 in response to iron deprivation.

Eric S Anderson, James T Paulley, R Martin Roop

Abstract read
In one paragraph

Article in Journal of bacteriology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Metal acquisition and virulence in Brucella.Animal health research reviews · 2012
    Review
  8. Article
  9. Article
  10. Article
  11. Intracellular adaptation of Brucella abortus.Journal of proteome research · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eric S AndersonDepartment of Microbiology and Immunology, East Carolina University School of Medicine, 600 Moye Boulevard, Greenville, NC 27834, USA.
James T Paulley
R Martin Roop

Funding

Brucella Iron Metabolism in Host MacrophagesR01AI063516 · NIAID · EAST CAROLINA UNIVERSITY · PI ROOP, ROY M · 2006 to 2010
$1.5M
NIAID NIH HHS AI 63516NIAID NIH HHS R01 AI063516
6 · The paper itself

Abstract

Phenotypic evaluation of isogenic mutants derived from Brucella abortus 2308 indicates that the AlcR homolog DhbR (2,3-dihydroxybenzoic acid [2,3-DHBA] biosynthesis regulator) modulates the expression of the genes involved in 2,3-DHBA production, employing 2,3-DHBA or brucebactin as a coinducer.

Indexed as

AraC Transcription FactorBase SequenceBrucella abortusGene Expression Regulation, BacterialHydroxybenzoatesIronModels, GeneticMolecular Sequence DataPolymerase Chain ReactionPromoter Regions, GeneticProtein BindingSiderophores2,3-dihydroxybenzoic acidAraC Transcription FactorHydroxybenzoatesIronSiderophores

Identifiers

PMID18156262
PMCPMC2258684

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.