Evidence map›Paper›PMID 18154668›Full record

SynthesisBMC public health2007

The global distribution of fatal pesticide self-poisoning: systematic review.

David Gunnell, Michael Eddleston, Michael R Phillips, Flemming Konradsen

2 registry-linked trialsOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in BMC public health, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 275 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
275citing papers in PubMed, 5 pooled it
35.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02160548 phase3completednot on this mapstarted 2015, after this paper: background citation

Effect of Adding Nebulized Salbutamol to Intravenous Atropine and Oxygen During Resuscitation of OP Pesticide Poisoned Patients

TypeinterventionalSponsorSylhet M.A.G.Osmani Medical CollegeRan2015 to 2015Enrolled75ConditionsOrganophosphate PoisoningArmsStandard care, Standard care+ 2.5 mg Salbutamol, Standard care+ 5 mg Salbutamol
NCT03597438 completednot on this mapstarted 2018, after this paper: background citation

Mitochondrial Targeted Biofuels as Countermeasures Against Chemical Threats

TypeobservationalSponsorChildren's Hospital of PhiladelphiaRan2018 to 2024Enrolled236ConditionsMitochondrial Alteration
3 · Its place in the literature

Who cites it

275 citing papers in PubMed, 5 syntheses or guidelines pooled it, 944 citations in OpenAlex.

  1. Pooled it
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  5. Pooled it
  6. Targeting Mitochondrial Dysfunction in Acute Organophosphate Toxicity: A Preliminary Evaluation of Cyclosporine A.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2026
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  13. Paraquat Peril: A Retrospective Study from the Frontlines of a Quaternary Care Hospital in South India.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
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  14. Observational
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215 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 4 countries.

David GunnellDepartment of Social Medicine, University of Bristol, Bristol, UK. d.j.gunnell@bristol.ac.uk
Michael Eddleston
Michael R Phillips
Flemming Konradsen
MRC Toxicology Unit · GBBeijing HuiLongGuan Hospital · CNUniversity of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvidence is accumulating that pesticide self-poisoning is one of the most commonly used methods of suicide worldwide, but the magnitude of the problem and the global distribution of these deaths is unknown.

methodsWe have systematically reviewed the worldwide literature to estimate the number of pesticide suicides in each of the World Health Organisation's six regions and the global burden of fatal self-poisoning with pesticides. We used the following data sources: Medline, EMBASE and psycINFO (1990-2007), papers cited in publications retrieved, the worldwide web (using Google) and our personal collections of papers and books. Our aim was to identify papers enabling us to estimate the proportion of a country's suicides due to pesticide self-poisoning.

resultsWe conservatively estimate that there are 258,234 (plausible range 233,997 to 325,907) deaths from pesticide self-poisoning worldwide each year, accounting for 30% (range 27% to 37%) of suicides globally. Official data from India probably underestimate the incidence of suicides; applying evidence-based corrections to India's official data, our estimate for world suicides using pesticides increases to 371,594 (range 347,357 to 439,267). The proportion of all suicides using pesticides varies from 4% in the European Region to over 50% in the Western Pacific Region but this proportion is not concordant with the volume of pesticides sold in each region; it is the pattern of pesticide use and the toxicity of the products, not the quantity used, that influences the likelihood they will be used in acts of fatal self-harm.

conclusionPesticide self-poisoning accounts for about one-third of the world's suicides. Epidemiological and toxicological data suggest that many of these deaths might be prevented if (a) the use of pesticides most toxic to humans was restricted, (b) pesticides could be safely stored in rural communities, and (c) the accessibility and quality of care for poisoning could be improved.

Indexed as

Global HealthHumansIncidencePesticidesPoisoningSafetySuicideSuicide PreventionPesticides

Identifiers

PMID18154668
PMCPMC2262093
OpenAlexW2149111967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.