Evidence map›Paper›PMID 18154314›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2008

Improved surface modification approach for micromechanical biosensors.

Hongyan Gao, Koutilya R Buchapudi, Abraham Harms-Smyth, Marvin K Schulte, Xiaohe Xu, Hai-Feng Ji

Abstract readValidation Study
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hongyan GaoChemistry, Institute for Micromanufacturing, Louisiana Tech University, Ruston, Louisiana 71272, USA.
Koutilya R Buchapudi
Abraham Harms-Smyth
Marvin K Schulte
Xiaohe Xu
Hai-Feng Ji

Funding

VIROLOGISTP20RR016466 · NCRR · UNIVERSITY OF ALASKA FAIRBANKS · PI KREBS, JOCELYN E · 2001 to 2011
$37.0M
Microcantilever Biosensors Based on Ligand Gated Ion Channel ReceptorsR01NS057366 · NINDS · UNIVERSITY OF ALASKA FAIRBANKS · PI SCHULTE, MARVIN KENNETH · 2008 to 2010
$969k
NCRR NIH HHS 5P20RR016466NCRR NIH HHS P20 RR016466NINDS NIH HHS R01 NS057366
6 · The paper itself

Abstract

We have investigated the sensing performance of protein-based microcantilever biosensors prepared from multiple surface conjugation chemistries. The 11-mercaptoundecanoic acid monolayers were prepared according to both traditional and modified processes. In three protein-based biosensors, the modified process improved microcantilever sensing performance by increasing the bending amplitude, a critical step toward developing a cost-effective microcantilever-based sensor platform for medical diagnostics and environmental and drug screening applications. Scanning electron microscopy (SEM) images demonstrated that proteins immobilized on the microcantilever surface using the modified chemistry approach formed a compact layer.

Indexed as

Biosensing TechniquesMicroscopy, Electron, ScanningReproducibility of ResultsSensitivity and SpecificitySurface Properties

Identifiers

PMID18154314
PMCPMC3633073

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.