ArticleBMC plant biology2007
TaMSH7: a cereal mismatch repair gene that affects fertility in transgenic barley (Hordeum vulgare L.).
Article in BMC plant biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 55 citations in OpenAlex.
- An overview of recent advances on wheat homologous and homoeologous recombination.Journal of experimental botany · 2026Review
- Functional analyses of homoeologous pericentromeric cohesion protective genes TaSGO1s during meiosis in Triticum aestivum.BMC plant biology · 2026Article
- Investigation of mechanisms underlying seedlessness in a Sangiovese somatic variant through comparative genomic and histological analyses.BMC plant biology · 2025Article
- Accumulation ofFrontiers in plant science · 2025Article
- MSH7 confers quantitative variation in pollen fertility and boosts grain yield in maize.Plant biotechnology journal · 2024Article
- Review
- Effective RNAi-Mediated Silencing of theGenes · 2021Article
- A major quantitative trait locus on chromosome A9, BnaPh1, controls homoeologous recombination in Brassica napus.The New phytologist · 2021Article
- Ph2 encodes the mismatch repair protein MSH7-3D that inhibits wheat homoeologous recombination.Nature communications · 2021Article
- Downregulation of BarleyFrontiers in plant science · 2021Article
- A Co-Expression Network in Hexaploid Wheat Reveals Mostly Balanced Expression and Lack of Significant Gene Loss of Homeologous Meiotic Genes Upon Polyploidization.Frontiers in plant science · 2019Article
- MutS-Homolog2 silencing generates tetraploid meiocytes in tomato (Plant direct · 2018Article
- The role of a cytosolic superoxide dismutase in barley-pathogen interactions.Molecular plant pathology · 2017Article
- DNA damage and repair in plants - from models to crops.Frontiers in plant science · 2015Review
- The isolation and characterisation of the wheat molecular ZIPper I homologue, TaZYP1.BMC research notes · 2012Article
- Research on plants for the understanding of diseases of nuclear and mitochondrial origin.Journal of biomedicine & biotechnology · 2012Review
- Poor Homologous Synapsis 1 Interacts with Chromatin but Does Not Colocalise with ASYnapsis 1 during Early Meiosis in Bread Wheat.International journal of plant genomics · 2012Article
- Effects of suppressing the DNA mismatch repair system on homeologous recombination in tomato.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2011Article
- High-level production of MSH2 from Arabidopsis thaliana: a DNA mismatch repair system key subunit.Molecular biotechnology · 2011Article
- Comparative Transcriptomics Reveals 129 Transcripts That Are Temporally Regulated during Anther Development and Meiotic Progression in Both Bread Wheat (Triticum aestivum) and Rice (Oryza sativa).International journal of plant genomics · 2011Article
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4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChromosome pairing, recombination and DNA repair are essential processes during meiosis in sexually reproducing organisms. Investigating the bread wheat (Triticum aestivum L.) Ph2 (Pairing homoeologous) locus has identified numerous candidate genes that may have a role in controlling such processes, including TaMSH7, a plant specific member of the DNA mismatch repair family.
resultsSequencing of the three MSH7 genes, located on the short arms of wheat chromosomes 3A, 3B and 3D, has revealed no significant sequence divergence at the amino acid level suggesting conservation of function across the homoeogroups. Functional analysis of MSH7 through the use of RNAi loss-of-function transgenics was undertaken in diploid barley (Hordeum vulgare L.). Quantitative real-time PCR revealed several T0 lines with reduced MSH7 expression. Positive segregants from two T1 lines studied in detail showed reduced MSH7 expression when compared to transformed controls and null segregants. Expression of MSH6, another member of the mismatch repair family which is most closely related to the MSH7 gene, was not significantly reduced in these lines. In both T1 lines, reduced seed set in positive segregants was observed.
conclusionResults presented here indicate, for the first time, a distinct functional role for MSH7 in vivo and show that expression of this gene is necessary for wild-type levels of fertility. These observations suggest that MSH7 has an important function during meiosis and as such remains a candidate for Ph2.
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