ReviewGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2007
Genetic detection of free cancer cells in the peritoneal cavity of the patient with gastric cancer: present status and future perspectives.
Review in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 67 citations in OpenAlex.
- Extended intraoperative peritoneal lavage as prophylactic peritoneal recurrence for locally advanced gastric cancer: a prospective randomized trial.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021Trial
- Impact of the number of colorectal cancer lymph node metastases on intraperitoneal lavage cytology: a multi-institutional, prospective, observational study.Surgery today · 2026Observational
- Prognostic factors in patients with gastric cancer and positive peritoneal cytology who underwent upfront surgery.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026Article
- Study protocol of a phase II clinical trial evaluating the efficacy of neoadjuvant intraperitoneal and systemic albumin-bound paclitaxel combined with camrelizumab and S-1 in the treatment of patients with exfoliative cell-positive gastric cancer.Frontiers in oncology · 2023Article
- Clinical importance of carcinoembryonic antigen messenger RNA level in peritoneal lavage fluids measured by transcription-reverse transcription concerted reaction for advanced gastric cancer in laparoscopic surgery.Surgical endoscopy · 2022Article
- Circulating methylated THBS1 DNAs as a novel marker for predicting peritoneal dissemination in gastric cancer.Journal of clinical laboratory analysis · 2021Article
- Impact of preoperative chemotherapy as initial treatment for advanced gastric cancer with peritoneal metastasis limited to positive peritoneal lavage cytology (CY1) or localized peritoneal metastasis (P1a): a multi-institutional retrospective study.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2021Article
- Impact of metabolism-related mutations on the heart rate of gastric cancer patients after peritoneal lavage.World journal of clinical cases · 2021Article
- Effects of differential distributed-JUP on the malignancy of gastric cancer.Journal of advanced research · 2021Article
- Reduced expression of exosomal miR‑29s in peritoneal fluid is a useful predictor of peritoneal recurrence after curative resection of gastric cancer with serosal involvement.Oncology reports · 2020Article
- The Significance of SCC and CEA mRNA in the Pleural Cavity After Lymphadenectomy in Esophageal Cancer Patients who Underwent Preoperative Treatment.World journal of surgery · 2018Article
- Intraoperative peritoneal lavage cytology offers prognostic significance for gastric cancer patients with curative resection.Cancer science · 2017Article
- Regional but fatal: Intraperitoneal metastasis in gastric cancer.World journal of gastroenterology · 2016Review
- Article
- Role of genetic detection in peritoneal washes with gastric carcinoma: The past, present and future.World journal of gastrointestinal oncology · 2016Review
- Intraoperative dissemination during gastrectomy for gastric cancer associated with serosal invasion.Surgery today · 2015Article
- Molecular diagnosis and therapy for occult peritoneal metastasis in gastric cancer patients.World journal of gastroenterology · 2014Review
- Article
- Circulating methylated MINT2 promoter DNA is a potential poor prognostic factor in gastric cancer.Digestive diseases and sciences · 2014Article
- Knockdown of hypoxia-inducible factor-1α accelerates peritoneal dissemination via the upregulation of MMP-1 expression in gastric cancer cell lines.Experimental and therapeutic medicine · 2012Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this review is to examine the current status and future perspectives of the molecular analysis of peritoneal lavage fluid in patients with gastric cancer. During the past 10 years, the polymerase chain reaction (PCR) has been applied for the molecular detection of free cancer cells in the abdominal cavity of patients with gastric cancer, and its clinical significance in establishing the presence of peritoneal dissemination has been assessed by several groups especially in Japan. The majority of these studies have confirmed the predictive value of the molecular detection of peritoneal metastasis and recurrence using peritoneal lavage fluid. Based on these findings, since April 2006, the genetic diagnosis of body fluids has been included in the Japanese Government public health insurance program for patients with solid tumors. However, there are still many obstacles to overcome before the genetic diagnosis of micrometastasis can be considered a routine laboratory assay. Here we review the importance of the molecular detection of cancer cells in the abdominal cavity, and the molecular techniques used for such diagnosis; we also provide some clinical examples to illustrate the value of molecular diagnosis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.