ArticleJournal of virology2008
Jaagsiekte sheep retrovirus utilizes a pH-dependent endocytosis pathway for entry.
Article in Journal of virology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 33 citations in OpenAlex.
- Acquisition and Exaptation of Endogenous Retroviruses in Mammalian Placenta.Biomolecules · 2023Review
- Deletion of the SARS-CoV-2 Spike Cytoplasmic Tail Increases Infectivity in Pseudovirus Neutralization Assays.Journal of virology · 2021Article
- Enzootic nasal tumor virus type 2 envelope of goats acts as a retroviral oncogene in cell transformation.Virus genes · 2021Article
- Infectious Entry Pathway Mediated by the Human Endogenous Retrovirus K Envelope Protein.Journal of virology · 2016Article
- A sorting signal suppresses IFITM1 restriction of viral entry.The Journal of biological chemistry · 2015Article
- HIV-1 entry in SupT1-R5, CEM-ss, and primary CD4+ T cells occurs at the plasma membrane and does not require endocytosis.Journal of virology · 2014Article
- IFITMs restrict the replication of multiple pathogenic viruses.Journal of molecular biology · 2013Review
- IFITM proteins restrict viral membrane hemifusion.PLoS pathogens · 2013Article
- Lentiviral vector gene transfer to porcine airways.Molecular therapy. Nucleic acids · 2012Article
- Critical role of leucine-valine change in distinct low pH requirements for membrane fusion between two related retrovirus envelopes.The Journal of biological chemistry · 2012Article
- Membrane fusion and cell entry of XMRV are pH-independent and modulated by the envelope glycoprotein's cytoplasmic tail.PloS one · 2012Article
- Retrovirus entry by endocytosis and cathepsin proteases.Advances in virology · 2012Article
- CD4-independent human immunodeficiency virus infection involves participation of endocytosis and cathepsin B.PloS one · 2011Article
- Cell entry of enveloped viruses.Advances in genetics · 2011Review
- Jaagsiekte sheep retrovirus biology and oncogenesis.Viruses · 2010Article
- Potentiating cancer immunotherapy using an oncolytic virus.Molecular therapy : the journal of the American Society of Gene Therapy · 2010Article
- Receptor binding and low pH coactivate oncogenic retrovirus envelope-mediated fusion.Journal of virology · 2009Article
- Low-pH triggering of human metapneumovirus fusion: essential residues and importance in entry.Journal of virology · 2009Article
- Enzootic nasal tumor virus envelope requires a very acidic pH for fusion activation and infection.Journal of virology · 2008Article
- Fusogenicity of Jaagsiekte sheep retrovirus envelope protein is dependent on low pH and is enhanced by cytoplasmic tail truncations.Journal of virology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Using Moloney murine leukemia virus pseudovirions bearing the envelope protein of Jaagsiekte sheep retrovirus (JSRV), we report here that entry was weakly inhibited by lysosomotropic agents but was profoundly blocked by bafilomycin A1 (BafA1). Kinetics studies revealed that JSRV entry is a slow process and was substantially blocked by a dominant-negative mutant of dynamin. Interestingly, a low-pH pulse overcame the BafA1 block to JSRV infection, although this occurred only if virus-bound cells were preincubated at 37 degrees C, consistent with a very early entry event such as endocytosis being required before the low-pH-dependent step occurs. Moreover, JSRV pseudovirions were resistant to low-pH inactivation. Altogether, this study reveals that JSRV utilizes a pH-dependent, dynamin-associated endocytosis pathway for entry that differs from the classical pH-dependent entry pathway of vesicular stomatitis virus.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.