ReviewCurrent opinion in neurobiology2007
Techniques for extracting single-trial activity patterns from large-scale neural recordings.
Review in Current opinion in neurobiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.
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Who cites it
86 citing papers in PubMed.
- The Importance of Synchrony in the Neural Control of Movement.bioRxiv : the preprint server for biology · 2026Article
- Motor cortex flexibly deploys a high-dimensional repertoire of subskills.bioRxiv : the preprint server for biology · 2025Article
- Beta-band desynchronization in the human hippocampus during movement preparation in a delayed reach task.Experimental brain research · 2025Article
- Article
- Mixed Representations of Sound and Action in the Auditory Midbrain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Computational role of structure in neural activity and connectivity.Trends in cognitive sciences · 2024Review
- Preparatory activity and the expansive null-space.Nature reviews. Neuroscience · 2024Review
- Mixed representations of sound and action in the auditory midbrain.bioRxiv : the preprint server for biology · 2023Article
- Synchrony-Division Neural Multiplexing: An Encoding Model.Entropy (Basel, Switzerland) · 2023Article
- Integrated neural dynamics of sensorimotor decisions and actions.PLoS biology · 2022Article
- Tools to measure membrane potential of neurons.Biomedical journal · 2022Review
- Cortical Control of Virtual Self-Motion Using Task-Specific Subspaces.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Statistical neuroscience in the single trial limit.Current opinion in neurobiology · 2021Review
- Causal Network Inference for Neural Ensemble Activity.Neuroinformatics · 2021Article
- Monosynaptic inference via finely-timed spikes.Journal of computational neuroscience · 2021Article
- Frequency-separated principal component analysis of cortical population activity.Journal of neurophysiology · 2020Article
- Identifying nonlinear dynamical systems via generative recurrent neural networks with applications to fMRI.PLoS computational biology · 2019Article
- Thirst regulates motivated behavior through modulation of brainwide neural population dynamics.Science (New York, N.Y.) · 2019Article
- Dynamics of motor cortical activity during naturalistic feeding behavior.Journal of neural engineering · 2019Article
- Structure and variability of delay activity in premotor cortex.PLoS computational biology · 2019Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Large, chronically implanted arrays of microelectrodes are an increasingly common tool for recording from primate cortex and can provide extracellular recordings from many (order of 100) neurons. While the desire for cortically based motor prostheses has helped drive their development, such arrays also offer great potential to advance basic neuroscience research. Here we discuss the utility of array recording for the study of neural dynamics. Neural activity often has dynamics beyond that driven directly by the stimulus. While governed by those dynamics, neural responses may nevertheless unfold differently for nominally identical trials, rendering many traditional analysis methods ineffective. We review recent studies - some employing simultaneous recording, some not - indicating that such variability is indeed present both during movement generation and during the preceding premotor computations. In such cases, large-scale simultaneous recordings have the potential to provide an unprecedented view of neural dynamics at the level of single trials. However, this enterprise will depend not only on techniques for simultaneous recording but also on the use and further development of analysis techniques that can appropriately reduce the dimensionality of the data, and allow visualization of single-trial neural behavior.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.