ArticleNeuron2007
A crystal-clear interaction: relating neuroligin/neurexin complex structure to function at the synapse.
Article in Neuron, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 17 citations in OpenAlex.
- High-Resolution Fluorescence Imaging Combined With Computer Simulations to Quantitate Surface Dynamics and Nanoscale Organization of Neuroligin-1 at Synapses.Frontiers in synaptic neuroscience · 2022Article
- Stochastic, structural and functional factors influencing AMPA and NMDA synaptic response variability: a review.Neuronal signaling · 2017Review
- Role of Neurexin-1β and Neuroligin-1 in Cognitive Dysfunction After Subarachnoid Hemorrhage in Rats.Stroke · 2015Article
- Variations analysis of NLGN3 and NLGN4X gene in Chinese autism patients.Molecular biology reports · 2014Article
- A matter of balance: role of neurexin and neuroligin at the synapse.Neurochemical research · 2013Review
- Medical conditions in autism spectrum disorders.Journal of neurodevelopmental disorders · 2009Article
- Activity-independent and subunit-specific recruitment of functional AMPA receptors at neurexin/neuroligin contacts.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice.Autism research : official journal of the International Society for Autism Research · 2008Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuronal circuits are maintained by homeostatic mechanisms controlling synapse maturation and signaling. Neuroligins (NLs) and neurexins (Nrxs) may regulate the fine balance between excitation and inhibition. In this issue of Neuron, Araç et al. and Fabrichny et al. define crystal structures of NLs bound to beta-Nrx, providing insights into their synaptic actions and clarifying structural defects associated with autism-linked mutations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.