ArticleJournal of burns and wounds2007
The increasing problem of wound bacterial burden and infection in acute and chronic soft-tissue wounds caused by methicillin-resistant Staphylococcus aureus.
Article in Journal of burns and wounds, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 55 citations in OpenAlex.
- Bioactive Hydrogels with D-Amino Acid RGD Mimics: A Therapeutic Strategy for Expeditious Infected Wound Closure.Advanced healthcare materials · 2026Article
- Oxygen and ROS Delivery for Infected Wound Healing and Future Prospects.Advanced healthcare materials · 2026Review
- Drug Susceptibility, Siderophore Production, and Genome Analysis ofAntibiotics (Basel, Switzerland) · 2025Article
- Clinical Characteristics and Treatment Outcomes of Pediatric Bacterial Skin and Soft Tissue Infections in Central Vietnam: A Prospective Study.Global pediatric health · 2024Article
- Bacterial Interactions in the Context of Chronic Wound Biofilm: A Review.Microorganisms · 2022Review
- Bacterial Cellulose: Functional Modification and Wound Healing Applications.Advances in wound care · 2021Article
- Infection control measures in nosocomial MRSA outbreaks-Results of a systematic analysis.PloS one · 2021Article
- Metabolic modelling of chronic wound microbiota predicts mutualistic interactions that drive community composition.Journal of applied microbiology · 2019Article
- Pullulan nanofibers containing the antimicrobial palindromic peptide LfcinB (21-25)RSC advances · 2019Article
- Molecular Characteristics of Methicillin-ResistantIranian journal of pathology · 2019Article
- Biofilm is a Major Virulence Determinant in Bacterial Colonization of Chronic Skin Ulcers Independently from the Multidrug Resistant Phenotype.International journal of molecular sciences · 2017Article
- Article
- Staphylococcus aureus induces hypoxia and cellular damage in porcine dermal explants.Infection and immunity · 2015Article
- Bacterial isolates from infected wounds and their antibiotic susceptibility pattern: some remarks about wound infection.International wound journal · 2015Article
- Risk factors for methicillin-resistant Staphylococcus aureus in diabetic foot infections.Diabetic foot & ankle · 2014Article
- Pharmacokinetics, pharmacodynamics and efficacy of novel FabI inhibitor AFN-1252 against MSSA and MRSA in the murine thigh infection model.Journal of chemotherapy (Florence, Italy) · 2013Article
- Multidrug-resistant organisms, wounds and topical antimicrobial protection.International wound journal · 2012Article
- Innate immune dysfunctions in aged mice facilitate the systemic dissemination of methicillin-resistant S. aureus.PloS one · 2012Article
- Community-acquired methicillin-resistant Staphylococcus aureus: community transmission, pathogenesis, and drug resistance.Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2010Review
- Preliminary proteomic analysis of circulating polymorphonuclear neutrophils from rabbits experiencing scald injury and Staphylococcus aureus sepsis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledMethicillin-resistant Staphylococcus aureus (MRSA) has become a leading cause of colonization and infection in both acute and chronic soft-tissue wounds.
objectiveOur objective is to define this current epidemic problem caused by both community-acquired MRSA (CA-MRSA) and hospital-acquired MRSA (HA-MRSA), focusing on the similarities and differences between these 2 isolates as well as the impact on wound management decisions.
methodsMethods used include a literature review on the growth of the current MRSA problem and its International scope. In addition, a current up-to-date assessment had been made of the problem and the current approach to management of MRSA in acute soft-tissue and chronic wounds. Burns are not discussed because this injury usually does not fit either categories and is managed quite uniquely.
resultsResults included the following: (1) There are very distinct properties of CA-MRSA and HA-MRSA, which must be considered for acute and chronic wound care. Management of both requires rigorous barrier precaution techniques to avoid cross-contamination. The presence of MRSA as a carrier state increases the risk of both a systemic and local wound infection in the carrier. There are large and increasing reservoirs of CA-MRSA and HA-MRSA worldwide leading to more bacteremias and wound problems. Topical antimicrobial therapy has not been addressed in managing MRSA in acute and chronic wounds.
conclusionConclusions include the fact that both HA-MRSA and CA-MRSA wound infections are rapidly increasing, especially with CA-MRSA. This high incidence requires appropriate wound prediction and management decisions as well as attempts to avoid further cross-contamination and reservoir growth. Topical antimicrobial therapy would seem to be an important component in controlling this tremendous problem. Yet this topic has yet to be adequately addressed.
Identifiers
18091985PMC2104747W2170552392What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.