ArticleEuropean journal of clinical nutrition2009
Relationship between long-chain polyunsaturated fatty acids at birth and motor function at 7 years of age.
Article in European journal of clinical nutrition, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 59 citations in OpenAlex.
- Impact of the n-6:n-3 long-chain PUFA ratio during pregnancy and lactation on offspring neurodevelopment: 5-year follow-up of a randomized controlled trial.European journal of clinical nutrition · 2017Trial
- Erythrocyte DHA and AA in infancy is not associated with developmental status and cognitive functioning five years later in Nepalese children.Nutrition journal · 2018Article
- Physiological and Biochemical Changes Reveal Differential Patterns of Docosahexaenoic Acid Partitioning in Two Marine Algal Strains of Isochrysis.Marine drugs · 2017Article
- Prenatal fish oil supplementation and early childhood development in the Upstate KIDS Study.Journal of developmental origins of health and disease · 2017Observational
- Polyunsaturated Fatty Acid Levels in Maternal Erythrocytes of Japanese Women during Pregnancy and after Childbirth.Nutrients · 2017Article
- Detection and treatment of omega-3 fatty acid deficiency in psychiatric practice: Rationale and implementation.Lipids in health and disease · 2016Review
- Role of perinatal long-chain omega-3 fatty acids in cortical circuit maturation: Mechanisms and implications for psychopathology.World journal of psychiatry · 2015Review
- A review of environmental contributions to childhood motor skills.Journal of child neurology · 2014Review
- Docosahexaenoic acid in maternal and neonatal plasma phospholipids and milk lipids of Taiwanese women in Kinmen: fatty acid composition of maternal blood, neonatal blood and breast milk.Lipids in health and disease · 2013Article
- Review
- Neurophysiologic and neurobehavioral evidence of beneficial effects of prenatal omega-3 fatty acid intake on memory function at school age.The American journal of clinical nutrition · 2011Article
- Maternal fatty acid status during pregnancy and lactation and relation to newborn and infant status.Maternal & child nutrition · 2011Review
- Early determinants of development: a lipid perspective.The American journal of clinical nutrition · 2009Review
- Docosahexaenoic acid supplementation in pregnancy and lactation.The American journal of clinical nutrition · 2009Review
- Maternal DHA levels and toddler free-play attention.Developmental neuropsychology · 2009Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesLong-chain polyunsaturated fatty acids (LCPUFA) rapidly accumulate in the central nervous system (CNS) during the perinatal CNS growth spurt. This particularly concerns arachidonic acid (AA: 20:4n-6) and docosahexaenoic acid (DHA: 22:6n-3), which are thought to play important roles in CNS development and function. The aim of this study was to investigate the relation between motor function at 7 years of age and the levels of AA and DHA in umbilical venous plasma phospholipids, representing the prenatal availability of these fatty acids, and in plasma phospholipids sampled at age 7 years. SUBJECTS/
methodsMotor function was assessed both quantitatively (the ability to perform a movement) and qualitatively (how the movement is performed) with the Maastricht Motor Test (MMT) in 306 children, born at term, at 7 years of age as part of a follow-up study.
resultsBackward stepwise multiple regression analyses revealed a significant, positive relation between umbilical plasma DHA concentrations (but not plasma DHA levels at 7 years) and the MMT total and quality score, corrected for the covariables gender, cognitive performance, gestational age and age at measurement (partial beta=0.13, P=0.01 and 0.14, P=0.01, respectively). The contributions of DHA and AA (both at birth and at 7 years of age) to quantitative movement scores were not significant.
conclusionsOur results suggest that prenatal DHA availability, which can be influenced by maternal dietary DHA intake during pregnancy, can have an effect on quality of movement in later life.
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