Evidence map›Paper›PMID 18091423›Full record

ArticleEpidemiology (Cambridge, Mass.)2008

Seven deadly sins of environmental epidemiology and the virtues of precaution.

Philippe Grandjean

Abstract read
In one paragraph

Article in Epidemiology (Cambridge, Mass.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. What is useful research? The good, the bad, and the stable.Environmental health : a global access science source · 2020
    Article
  3. Review
  4. Paracelsus Revisited: The Dose Concept in a Complex World.Basic & clinical pharmacology & toxicology · 2016
    Review
  5. Critical complexity in environmental health practice: simplify and complexify.Environmental health : a global access science source · 2012
    Review
  6. Article
  7. Article
  8. Article
  9. Workshop on ethics and communication in Copenhagen 11-13.3.2007.Environmental health : a global access science source · 2008
    Article
  10. Late insights into early origins of disease.Basic & clinical pharmacology & toxicology · 2008
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Philippe GrandjeanDepartment of Environmental Medicine, University of Southern Denmark, Odense, Denmark. pgrand@hsph.harvard.edu

Funding

Epidemiology of Immunotoxicant Exposure in ChildrenR01ES012199 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI GRANDJEAN, PHILIPPE ADAM · 2004 to 2015
$3.4M
MERCURY-ASSOCIATED NEUROBEHAVIORAL DEFICIT IN CHILDRENU01ES009797 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI GRANDJEAN, PHILIPPE ADAM · 2000 to 2004
$2.1M
Mercury-Associated Neurobehavioral Deficit in ChildrenR01ES009797 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI GRANDJEAN, PHILIPPE ADAM · 2007 to 2011
$2.0M
Effects of perinatal endocrine disrupters in childrenR01ES011681 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI GRANDJEAN, PHILIPPE ADAM · 2001 to 2004
$1.3M
NIEHS NIH HHS ES09797NIEHS NIH HHS ES11681NIEHS NIH HHS ES12199NIEHS NIH HHS R01 ES009797NIEHS NIH HHS R01 ES011681NIEHS NIH HHS R01 ES012199
6 · The paper itself

Abstract

The potentials for error in planning, conducting, reporting, and utilizing epidemiologic results can be considered in terms of the traditional 7 deadly sins. To counter these sins, epidemiologic virtues should be inspired by the precautionary principle. The remedies emphasize acknowledgment and exploration of the impact of uncertainties, weight-of-the-evidence assessments that consider what could be known given the opportunities for research, and epidemiologic strategies that facilitate the use of tentative, though innovative, studies in decision-making.

Indexed as

Environmental ExposureEpidemiologic Research DesignBiasHumansRisk Assessment

Identifiers

PMID18091423
PMCPMC2639782

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.