Evidence map›Paper›PMID 18087761›Full record

ArticleClinical rheumatology2008

Anticitrulline peptide antibodies (CCP3) in leprosy sera: a negative association.

Luiz Sergio Guedes-Barbosa, Cristovão Mangueira, Morton Scheinberg

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Luiz Sergio Guedes-BarbosaUniversidade Federal Mato Grosso, Mato Grosso, Brazil. lsguedes@brturbo.com.br
Cristovão Mangueira
Morton Scheinberg
Hospital Israelita Albert Einstein · BRUniversidade do Estado de Mato Grosso · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anticyclic citrullinated peptide antibodies (anti-CCP) have been described almost exclusively in patients with rheumatoid arthritis. Recently, these autoantibodies have been found in patients with active tuberculosis. Leprosy is another mycobacterial disease where the presence of autoantibodies has been described by several authors. In this study, 64 patients with leprosy (32 paucibacillary and 32 multibacillary forms of the disease) were evaluated and only 2 patients were positive for the presence of anti-CCP. The low frequency of anti-CCP in leprosy sera demonstrated in our study illustrates the high specificity of anti-CCP for the diagnosis of rheumatoid arthritis.

Indexed as

AdolescentAdultArthritis, RheumatoidAutoantibodiesBiomarkersDiagnosis, DifferentialFemaleHumansLeprosyMaleMiddle AgedPeptides, CyclicSensitivity and SpecificityAutoantibodiesBiomarkerscyclic citrullinated peptidePeptides, Cyclic

Identifiers

PMID18087761
OpenAlexW1974512065

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.