Evidence map›Paper›PMID 18087583›Full record

ReviewEnvironmental health perspectives2007

Electrochemical sensors for the detection of lead and other toxic heavy metals: the next generation of personal exposure biomonitors.

Wassana Yantasee, Yuehe Lin, Kitiya Hongsirikarn, Glen E Fryxell, Raymond Addleman, Charles Timchalk

Open access · diamondAbstract readReview
In one paragraph

Review in Environmental health perspectives, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
6.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 178 citations in OpenAlex.

  1. Article
  2. Review
  3. On-chip trace detection of CdCommunications engineering · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
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  14. Review
  15. Article
  16. Noninvasive wearable electroactive pharmaceutical monitoring for personalized therapeutics.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Wassana YantaseePacific Northwest National Laboratory, Richland, WA 99352, USA.
Yuehe Lin
Kitiya Hongsirikarn
Glen E Fryxell
Raymond Addleman
Charles Timchalk
Pacific Northwest National Laboratory · US

Funding

INNOVATIVE BIOMONITORING FOR LEAD IN SALIVAR01ES010976 · NIEHS · BATTELLE PACIFIC NORTHWEST LABORATORIES · PI TIMCHALK, CHARLES · 2003 to 2006
$929k
Portable Analyzer for On-site Monitoring of Worker Exposure to Toxic MetalsR21OH008900 · OH · BATTELLE PACIFIC NORTHWEST LABORATORIES · PI TIMCHALK, CHARLES · 2006 to 2007
$397k
NIEHS NIH HHS 1R01 ES10976-04NIEHS NIH HHS R01 ES010976NIOSH CDC HHS 1R21 OH008900-01NIOSH CDC HHS R21 OH008900
6 · The paper itself

Abstract

To support the development and implementation of biological monitoring programs, we need quantitative technologies for measuring xenobiotic exposure. Microanalytical based sensors that work with complex biomatrices such as blood, urine, or saliva are being developed and validated and will improve our ability to make definitive associations between chemical exposures and disease. Among toxic metals, lead continues to be one of the most problematic. Despite considerable efforts to identify and eliminate Pb exposure sources, this metal remains a significant health concern, particularly for young children. Ongoing research focuses on the development of portable metal analyzers that have many advantages over current available technologies, thus potentially representing the next generation of toxic metal analyzers. In this article, we highlight the development and validation of two classes of metal analyzers for the voltammetric detection of Pb, including: a) an analyzer based on flow injection analysis and anodic stripping voltammetry at a mercury-film electrode, and b) Hg-free metal analyzers employing adsorptive stripping voltammetry and novel nanostructure materials that include the self-assembled monolayers on mesoporous supports and carbon nanotubes. These sensors have been optimized to detect Pb in urine, blood, and saliva as accurately as the state-of-the-art inductively coupled plasma-mass spectrometry with high reproducibility, and sensitivity allows. These improved and portable analytical sensor platforms will facilitate our ability to conduct biological monitoring programs to understand the relationship between chemical exposure assessment and disease outcomes.

Indexed as

Environmental ExposureAnimalsBiosensing TechniquesElectrochemistryElectrodesFlow Injection AnalysisHumansLeadLeadbiomonitoringdosimetry technologyelectrochemical sensorsexposure assessmentlead (Pb)

Identifiers

PMID18087583
PMCPMC2137133
OpenAlexW2047356169

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.