Evidence map›Paper›PMID 18086524›Full record

ArticleBioorganic & medicinal chemistry letters2008

Glycopolydiacetylene nanoparticles as a chromatic biosensor to detect Shiga-like toxin producing Escherichia coli O157:H7.

Jon O Nagy, Yalong Zhang, Wen Yi, Xianwei Liu, Edwin Motari, Jing Catherine Song, Jeffrey T Lejeune, Peng George Wang

Open access · greenAbstract read
In one paragraph

Article in Bioorganic & medicinal chemistry letters, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 37 citations in OpenAlex.

  1. Carbohydrate-based biosensors for enhanced pathogen detection.Analytical and bioanalytical chemistry · 2026
    Review
  2. Review
  3. Review
  4. Review
  5. Glyconanomaterials for Combating Bacterial Infections.Chemistry (Weinheim an der Bergstrasse, Germany) · 2015
    Article
  6. Polymeric lipid assemblies as novel theranostic tools.Accounts of chemical research · 2011
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jon O NagyATERIS Technologies, Bozeman, MT 59718, USA. wang.892@osu.edu
Yalong Zhang
Wen Yi
Xianwei Liu
Edwin Motari
Jing Catherine Song
Jeffrey T Lejeune
Peng George Wang
The Ohio State University · USMontana State University · US

Funding

Development of a selective biosensor for detecting organophosphate exposureU44NS058229 · NINDS · NAGY CONSULTING · PI NAGY, JON OWEN · 2006 to 2009
$2.6M
Development of a selective biosensor for detecting organophosphate pesticide expoR43ES016392 · NIEHS · ATERIS TECHNOLOGIES, LLC · PI NAGY, JON OWEN · 2007 to 2008
$597k
NIEHS NIH HHS R43 ES016392NINDS NIH HHS U44 NS058229NINDS NIH HHS U44NS058229-01
6 · The paper itself

Abstract

Shiga toxin-producing Escherichia coli organisms (STEC) were detected by Gal-alpha1,4-Gal glycopolydiacetylene (GPDA) nanoparticles through the selective binding between Shiga toxin and GPDA nanoparticles. The binding produced a colorimetric change in the absorption wavelength of the GPDA nanoparticles. This method provides a highly selective, rapid, sensitive, and quantitative approach for the detection of STEC.

Indexed as

Biosensing TechniquesNanoparticlesEscherichia coli O157Polyacetylene PolymerPolymersPolyynesShiga ToxinsPolyacetylene PolymerpolydiacetylenePolymersPolyynesShiga Toxins

Identifiers

PMID18086524
PMCPMC2839895
OpenAlexW2135954988

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.