ArticleBehavioral neuroscience2007
Experience-induced fetal plasticity: the effect of gestational ethanol exposure on the behavioral and neurophysiologic olfactory response to ethanol odor in early postnatal and adult rats.
Article in Behavioral neuroscience, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 58 citations in OpenAlex.
- Prenatal drug exposure, behavioral problems, and drug experimentation among African-American urban adolescents.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2014Trial
- Do Human Fetuses Form Long-Lasting Chemosensory Memories? Longitudinal Follow-Up From Fetus to Young Child of Facial Responses to Flavor/Odor Stimuli.Developmental psychobiology · 2026Article
- Effects of prenatal alcohol exposure on the olfactory system development.Frontiers in neural circuits · 2024Review
- Perinatal attention, memory and learningEnfance; psychologie, pedagogie, neuropsychiatrie, sociologie · 2021Article
- Article
- Olfaction scaffolds the developing human from neonate to adolescent and beyond.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Review
- Alterations in the whole brain network organization after prenatal ethanol exposure.The European journal of neuroscience · 2020Article
- Lingering Effects of Prenatal Alcohol Exposure on Basal and Ethanol-Evoked Expression of Inflammatory-Related Genes in the CNS of Adolescent and Adult Rats.Frontiers in behavioral neuroscience · 2020Article
- Fetal Alcohol Programming of Subsequent Alcohol Affinity: A Review Based on Preclinical, Clinical and Epidemiological Studies.Frontiers in behavioral neuroscience · 2020Review
- Functional Connectivity and Metabolic Alterations in Medial Prefrontal Cortex in a Rat Model of Fetal Alcohol Spectrum Disorder: A Resting-State Functional Magnetic Resonance Imaging and in vivo Proton Magnetic Resonance Spectroscopy Study.Developmental neuroscience · 2019Article
- Postnatal Exposure to Ethanol Increases Its Oral Acceptability to Adolescent Rats.Chemical senses · 2018Article
- Fetal alcohol exposure reduces responsiveness of taste nerves and trigeminal chemosensory neurons to ethanol and its flavor components.Journal of neurophysiology · 2017Article
- Prenatal Ethanol Exposure and Whisker Clipping Disrupt Ultrasonic Vocalizations and Play Behavior in Adolescent Rats.Brain sciences · 2016Article
- Neuronal pattern separation in the olfactory bulb improves odor discrimination learning.Nature neuroscience · 2015Article
- Unilateral whisker clipping exacerbates ethanol-induced social and somatosensory behavioral deficits in a sex- and age-dependent manner.Physiology & behavior · 2015Article
- Docosahexaenoic acid partially ameliorates deficits in social behavior and ultrasonic vocalizations caused by prenatal ethanol exposure.Behavioural brain research · 2015Article
- A comparison of the different animal models of fetal alcohol spectrum disorders and their use in studying complex behaviors.Frontiers in pediatrics · 2014Review
- Prenatal alcohol exposure increases postnatal acceptability of nicotine odor and taste in adolescent rats.PloS one · 2014Article
- The fine temporal structure of the rat licking pattern: what causes the variabiliy in the interlick intervals and how is it affected by the drinking solution?Chemical senses · 2013Article
- Impaired odor identification in children with histories of heavy prenatal alcohol exposure.Alcohol (Fayetteville, N.Y.) · 2013Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Human fetal ethanol exposure is strongly associated with ethanol avidity during adolescence. Evidence that intrauterine olfactory experience influences chemosensory-guided postnatal behaviors suggests that an altered response to ethanol odor resulting from fetal exposure may contribute to later abuse risk. Using behavioral and neurophysiological methods, the authors tested whether ethanol exposure via the dam's diet resulted in an altered responsiveness to ethanol odor in infant and adult rats. Compared with controls, (a) fetal exposure tuned the neurophysiologic response of the olfactory epithelium to ethanol odor at some expense to its responsiveness to other odorants in infantile rats--this effect was absent in adults; (b) the neural effect in infantile rats was paralleled by an altered behavioral response to ethanol odor that was specific to this odorant--this effect was also absent in adults; and (c) a significant component of the infantile behavioral effect was attributable to ethanol's effect on the olfactory neural modality. These data provide evidence for an important relationship between prenatal ethanol experience and postnatal behavioral responsiveness to the drug that is modulated or determined by olfactory function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.