Evidence map›Paper›PMID 18085381›Full record

ArticleMedical molecular morphology2007

Immunohistochemical phenotype of cutaneous cribriform carcinoma with a panel of 15 antibodies.

Angel Fernandez-Flores, Antonio Pol, Fernando Juanes, Luis G Crespo

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Medical molecular morphology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. S1 guideline sweat gland carcinoma.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
    Guideline
  2. Article
  3. Review
  4. Article
  5. Review
  6. Primary Cutaneous Cribriform Apocrine Carcinoma.The American journal of case reports · 2021
    Article
  7. A case of cribriform carcinoma of the skin: a newly described rare condition.Journal of pathology and translational medicine · 2021
    Article
  8. [Primary cutaneous cribriform apocrine carcinoma : An underdiagnosed entity?].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Angel Fernandez-FloresService of Anatomic Pathology, Clinica Ponferrada, Avenida Galicia 1, 24400 Ponferrada, Leon, Spain. gpyauflowerlion@terra.es
Antonio Pol
Fernando Juanes
Luis G Crespo
Hospital El Bierzo · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a cribriform carcinoma of the left fossa poplitea in a 62-year-old woman. The patient did not present any symptoms, and the only complaint was the nodule, which was resected for diagnosis. After considering different diagnostic options, we decided that the most appropriate one was cribriform carcinoma, which is an entity described in 1998. The diagnostic criteria, which were provided in the few publications that refer to this entity, helped us to distinguish it from the main mimicker: cystic adenoid carcinoma. Owing to the cribriform pattern of the tumor, we also looked for a metastasis from other sites, mainly breast, vulva, and salivary glands, but all these were clinically excluded. The tumoral cells showed secretion by decapitation, as well as a positive stain of the luminal secretion by histochemical techniques of Alcian blue and periodic acid-Schiff. The tumor was negative for iron stain. In spite of these characteristics, which are, for some authors, indicative of an apocrine phenotype, the immunohistochemical study revealed some differences with the profile that has been described in cases of apocrine adenocarcinoma. The tumor did not express GCDFP-15 or CD 15. It was also negative for SMA, CEA, and PR. The pattern of cytokeratins expressed by our case was positive for AE1-AE3, CAM 5.2, and CK7, without any expression for CK20. Other markers expressed by the tumor were EMA, ER, c-erbB-2, p53, and S-100.

Indexed as

AdenocarcinomaAntibodies, NeoplasmCell NucleolusFemaleHumansImmunohistochemistryMiddle AgedPhenotypeSkin NeoplasmsAntibodies, Neoplasm

Identifiers

PMID18085381
OpenAlexW1995118811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.