Evidence map›Paper›PMID 18084714›Full record

ArticleInfection2009

Clearance of chronic HCV infection during acute delta hepatitis.

K Deterding, S V Pothakamuri, V Schlaphoff, J Hadem, F Metzler, M J Bahr, M P Manns, M Cornberg, H Wedemeyer

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Infection, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 37 citations in OpenAlex.

  1. A novelJHEP reports : innovation in hepatology · 2025
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Hepatitis B virus and hepatitis C virus dual infection.World journal of gastroenterology · 2014
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

K DeterdingDept. of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Germany.
S V Pothakamuri
V Schlaphoff
J Hadem
F Metzler
M J Bahr
M P Manns
M Cornberg
H Wedemeyer
Medizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The course of chronic hepatitis C in acute HDV/HBV superinfection is unknown. Here, we report a patient with chronic hepatitis C who cleared HCV during acute self-limited hepatitis B/D superinfection. Recovery from HCV was associated with the appearance of a strong and multispecific HDV-specific memory CD4+ and CD8+ T cell response - but only weak HCV-specific CD4+ T cell responses. These data suggest that HCV can be cleared by bystander mechanisms during acute infections with other pathogens which may be considered in the development of immunotherapies for hepatitis C.

Indexed as

Acute DiseaseAdultAntiviral AgentsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesHepatitis BHepatitis C, ChronicHepatitis DHumansLamivudineLiver Function TestsMaleSubstance Abuse, IntravenousSuperinfectionAntiviral AgentsLamivudine

Identifiers

PMID18084714
OpenAlexW2090038764

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.