Evidence map›Paper›PMID 18083777›Full record

ArticleGenome research2008

Short read fragment assembly of bacterial genomes.

Mark J Chaisson, Pavel A Pevzner

Abstract readComparative Study
In one paragraph

Article in Genome research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 173 papers.

0numbers the graph read from it
0cells of the map it votes in
173citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

173 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Genome Characterization ofMicrobiology resource announcements · 2022
    Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Conducting metagenomic studies in microbiology and clinical research.Applied microbiology and biotechnology · 2018
    Review
  19. Review
  20. Article

113 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mark J ChaissonBioinformatics Program, University of California San Diego, La Jolla, California 92093, USA.
Pavel A Pevzner

Funding

Genome Sequencing by Ligation Using Nano-Arrays of Single DNA MoleculesR21HG004130 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HUANG, XIAOHUA · 2006 to 2007
$501k
NHGRI NIH HHS 1R21HG004130-01NHGRI NIH HHS R21 HG004130
6 · The paper itself

Abstract

In the last year, high-throughput sequencing technologies have progressed from proof-of-concept to production quality. While these methods produce high-quality reads, they have yet to produce reads comparable in length to Sanger-based sequencing. Current fragment assembly algorithms have been implemented and optimized for mate-paired Sanger-based reads, and thus do not perform well on short reads produced by short read technologies. We present a new Eulerian assembler that generates nearly optimal short read assemblies of bacterial genomes and describe an approach to assemble reads in the case of the popular hybrid protocol when short and long Sanger-based reads are combined.

Indexed as

AlgorithmsContig MappingGenome, BacterialGenomicsResearch DesignSequence Analysis, DNA

Identifiers

PMID18083777
PMCPMC2203630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.