ArticleBiology direct2007
Orthologs of the small RPB8 subunit of the eukaryotic RNA polymerases are conserved in hyperthermophilic Crenarchaeota and "Korarchaeota".
Article in Biology direct, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 41 citations in OpenAlex.
- Molecular Evolution of the Archaeal DNA-Dependent RNA Polymerase: Cooperative Changes in Subunit Composition and Specific Domains of Small Subunits.International journal of molecular sciences · 2026Article
- Structure of the recombinant RNA polymerase from African Swine Fever Virus.Nature communications · 2024Article
- Several Isoforms for Each Subunit Shared by RNA Polymerases are Differentially Expressed in the Cultivated Olive Tree (Frontiers in molecular biosciences · 2021Article
- Structure-Based Deep Mining Reveals First-Time Annotations for 46 Percent of the Dark Annotation Space of the 9,671-Member Superproteome of the Nucleocytoplasmic Large DNA Viruses.Journal of virology · 2020Article
- The cutting edge of archaeal transcription.Emerging topics in life sciences · 2018Article
- Archaea and the origin of eukaryotes.Nature reviews. Microbiology · 2017Review
- Molecular Mechanisms of Transcription Initiation-Structure, Function, and Evolution of TFE/TFIIE-Like Factors and Open Complex Formation.Journal of molecular biology · 2016Review
- Exploring microbial dark matter to resolve the deep archaeal ancestry of eukaryotes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015Article
- Origin of eukaryotes from within archaea, archaeal eukaryome and bursts of gene gain: eukaryogenesis just made easier?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015Review
- The dispersed archaeal eukaryome and the complex archaeal ancestor of eukaryotes.Cold Spring Harbor perspectives in biology · 2014Review
- Article
- Review
- Soaking of DNA into crystals of archaeal RNA polymerase achieved by desalting in droplets.Acta crystallographica. Section F, Structural biology and crystallization communications · 2012Article
- An archaeal origin for the actin cytoskeleton: Implications for eukaryogenesis.Communicative & integrative biology · 2011Article
- The evolution of the cytoskeleton.The Journal of cell biology · 2011Review
- Insights into the evolution of Archaea and eukaryotic protein modifier systems revealed by the genome of a novel archaeal group.Nucleic acids research · 2011Article
- The complete genome sequence of Thermoproteus tenax: a physiologically versatile member of the Crenarchaeota.PloS one · 2011Article
- Fidelity in archaeal information processing.Archaea (Vancouver, B.C.) · 2010Review
- Rearrangement of the RNA polymerase subunit H and the lower jaw in archaeal elongation complexes.Nucleic acids research · 2010Article
- The origin and early evolution of eukaryotes in the light of phylogenomics.Genome biology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Although most of the key components of the transcription apparatus, and in particular, RNA polymerase (RNAP) subunits, are conserved between archaea and eukaryotes, no archaeal homologs of the small RPB8 subunit of eukaryotic RNAP have been detected. We report that orthologs of RPB8 are encoded in all sequenced genomes of hyperthermophilic Crenarchaeota and a recently sequenced "korarchaeal" genome, but not in Euryarchaeota or the mesophilic crenarchaeon Cenarchaeum symbiosum. These findings suggest that all 12 core subunits of eukaryotic RNAPs were already present in the last common ancestor of the extant archaea.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.