ArticlePlant molecular biology2008
A gain-of-function mutation of transcriptional factor PTL results in curly leaves, dwarfism and male sterility by affecting auxin homeostasis.
Article in Plant molecular biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 52 citations in OpenAlex.
- Insights into the genetic bases of differential organ size in cactus flowers: a case study in two contrasting species.Annals of botany · 2026Article
- The SlDREBA4-SlASIL2 module mediates tomato thermotolerance by regulating the expression of SlHSP20/90.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Trihelix transcription factors: versatile regulators in plant growth and development, abiotic, and biotic stress responses.Plant cell reports · 2026Review
- Conservation and Divergence of the Trihelix Genes in Brassica and Expression Profiles ofInternational journal of molecular sciences · 2022Article
- Identification and in Silico Characterization of GT Factors Involved in Phytohormone and Abiotic Stresses Responses inInternational journal of molecular sciences · 2019Article
- Genome-wide identification and expression analysis of the trihelix transcription factor family in tartary buckwheat (Fagopyrum tataricum).BMC plant biology · 2019Article
- Genome-wide identification and expression profiling of trihelix gene family under abiotic stresses in wheat.BMC genomics · 2019Article
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- Comprehensive analysis of trihelix genes and their expression under biotic and abiotic stresses in Populus trichocarpa.Scientific reports · 2016Article
- Transcriptome-Wide Identification and Expression Profiling Analysis of Chrysanthemum Trihelix Transcription Factors.International journal of molecular sciences · 2016Article
- HANABA TARANU (HAN) Bridges Meristem and Organ Primordia Boundaries through PINHEAD, JAGGED, BLADE-ON-PETIOLE2 and CYTOKININ OXIDASE 3 during Flower Development in Arabidopsis.PLoS genetics · 2015Article
- Trihelix transcription factor GT-4 mediates salt tolerance via interaction with TEM2 in Arabidopsis.BMC plant biology · 2014Article
- Evolutionary history of trihelix family and their functional diversification.DNA research : an international journal for rapid publication of reports on genes and genomes · 2014Article
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- Efficient Transduction of LEDGF/p75 Mutant Cells by Gain-of-Function HIV-1 Integrase Mutant Viruses.Molecular therapy. Methods & clinical development · 2014Article
- Ectopic expression of a wheat WRKY transcription factor gene TaWRKY71-1 results in hyponastic leaves in Arabidopsis thaliana.PloS one · 2013Article
- Sex-specific DNA methylation and gene expression in andromonoecious poplar.Plant cell reports · 2012Article
- Identification and in silico characterization of soybean trihelix-GT and bHLH transcription factors involved in stress responses.Genetics and molecular biology · 2012Article
- Systematic analysis of GT factor family of rice reveals a novel subfamily involved in stress responses.Molecular genetics and genomics : MGG · 2010Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
GT factors are plant-specific trihelix DNA-binding transcription factors, which are involved in light responses and other developmental processes in plant. We identified a gain-of-function mutant of a GT-2 factor gene, PETAL LOSS (PTL), which displayed pleiotropic phenotypes including dwarfism, curly leaves, retarded growth and male sterility. We found that constitutive and ectopic over-expression of PTL driven by the CaMV 35S promoter could not recapitulate the phenotypes of the 35S enhancer-driven mutant ptl-D, and was lethal in some of the transgenic plants at the cotyledon developmental stage, suggesting that accurate temporal and spatial expression of PTL is essential for its proper functional implementation during plant development. Further analysis showed that ptl-D was defective in auxin action and that the alteration of auxin distribution corresponded to the curly leaf phenotype. The fact that degeneration of septum cells and subsequent breakage along the stomium was not observed in ptl-D anthers suggests that defective anther dehiscence was the cause for male sterility. Identification and characterization of the gain-of-function mutant ptl-D will improve our understanding of the diverse functions of GT factors during plant development.
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