Evidence map›Paper›PMID 18080192›Full record

ArticleDigestive diseases and sciences2008

Endoscopic patterns and histopathological features after eradication therapy in Helicobacter pylori-associated nodular gastritis.

Ming-Jen Chen, Shou-Chuan Shih, Tsang-En Wang, Yu-Jan Chan, Chih-Jen Chen, Wen-Hsiung Chang

Abstract read
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In one paragraph

Article in Digestive diseases and sciences, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. JGH open : an open access journal of gastroenterology and hepatology · 2020
    Article
  3. Article
  4. Article
  5. 'Goose bumps'-associated anaemia.BMJ case reports · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ming-Jen ChenDepartment of Gastroenterology, Mackay Memorial Hospital and Mackay Medicine, Nursing and Management College, No. 92, Sec. 2, Chung-Shan N. Road, Taipei 104, Taiwan, Republic of China. mingjen.ch@msa.hinet.net
Shou-Chuan Shih
Tsang-En Wang
Yu-Jan Chan
Chih-Jen Chen
Wen-Hsiung Chang
Mackay Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endoscopic finding of nodular gastritis (NG) is highly associated with presence of Helicobacter pylori infection. How the endoscopic patterns and histopathology of NG change after eradication of H. pylori is unclear. Twenty-one adults (3 men and 18 women) with H. pylori-associated NG found on endoscopy were enrolled for this study. The histological findings included gastritis activity, bacterial colonization, and lymphoid follicles. Repeat endoscopy for the endoscopic as well as histopathological features of gastric biopsy specimens was performed 2 months later after eradication treatment. H. pylori was successfully eradicated in 19 patients. Endoscopic NG disappeared in 12, improved in 5, and was unchanged in 4. After treatment, there was significant improvement in scores for gastritis activity [P < 0.001, 95% confidence interval (CI) 1.31-1.91], bacterial colonization (P < 0.001, 95% CI 0.71-1.14) and follicular gastritis (P = 0.047, 95% CI 0.04-0.52), primarily among patients whose endoscopic pattern resolved completely. The disappearance of nodularity on endoscopy was accompanied by a decrease in follicular gastritis score.

Indexed as

GastroscopyHelicobacter pylori2-PyridinylmethylsulfinylbenzimidazolesAdultAlkylating AgentsAmoxicillinAnti-Bacterial AgentsAnti-Ulcer AgentsBiopsyDrug Therapy, CombinationFemaleGastritisHelicobacter InfectionsHumansLansoprazoleMale2-PyridinylmethylsulfinylbenzimidazolesAlkylating AgentsAmoxicillinAnti-Bacterial AgentsAnti-Ulcer AgentsLansoprazoleTinidazole

Identifiers

PMID18080192
OpenAlexW1970777044

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.