ArticlePediatric cardiology2008
Medication dosing and renal insufficiency in a pediatric cardiac intensive care unit: impact of pharmacist consultation.
Article in Pediatric cardiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of clinical pharmacist interventions in paediatric hospital patients.European journal of pediatrics · 2018Pooled it
- Economic evaluations of clinical pharmacist interventions on hospital inpatients: a systematic review of recent literature.International journal of clinical pharmacy · 2014Pooled it
- Pharmacist Avoidance or Reductions in Medical Costs in Critically and Emergently Ill Pediatrics: PHARM-PEDS Study.Critical care explorations · 2023Article
- Hospital Pharmacists Interventions to Drug-Related Problems at Tertiary Critical Care Pediatric Settings in Jazan, Saudi Arabia.Hospital pharmacy · 2022Article
- Evaluation of pharmaceutical care in a diabetes ward from China: a pre-and post-intervention study.International journal of clinical pharmacy · 2016Article
- Pharmacist Remote Review of Medication Prescriptions for Appropriateness in Pediatric Intensive Care Unit.Frontiers in pharmacology · 2016Article
- Do we need a pharmacist in the ICU?Intensive care medicine · 2015Article
- Prophylactic ranitidine treatment in critically ill children--a population pharmacokinetic study.British journal of clinical pharmacology · 2013Article
- Pediatric drug-related problems: a multicenter study in four French-speaking countries.International journal of clinical pharmacy · 2013Article
- Recommendations for Meeting the Pediatric Patient's Need for a Clinical Pharmacist: A Joint Opinion of the Pediatrics Practice and Research Network of the American College of Clinical Pharmacy and the Pediatric Pharmacy Advocacy Group.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2012Article
- Medication dosing and renal insufficiency in a pediatric cardiac intensive unit.Pediatric cardiology · 2008Article
- Dosing of Appropriate Antibiotics and Time to Administration of First Doses in the Pediatric Emergency Department.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAGArticle
- Bisphosphonates for Osteoporosis in Patients with Renal Insufficiency: Pharmacists' Practices and Beliefs.The Canadian journal of hospital pharmacyArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pediatric patients who have undergone cardiac surgery are at risk for renal insufficiency. The impact of pharmacist consultation in the pediatric cardiac intensive care unit (ICU) has yet to be defined. Patients admitted to the pediatric cardiac ICU at our institution from January through March of 2006 were included. Patient information, collected retrospectively, included: demographics, cardiac lesion/surgery, height, weight, need for peritoneal or hemodialysis, need for mechanical support, highest and lowest serum creatinine, ICU length of stay (LOS), renally eliminated medications, pharmacist recommendations (accepted or not), and appropriateness of dosing changes.There were 140 total admissions (131 patients; age: 3.0 +/- 6.3 years) during the study period. In total, 14 classes of renally eliminated medications were administered, with 32.6 +/- 56.4 doses administered per patient admission. Thirty-seven patient admissions had one or more medications adjusted for renal insufficiency; the most commonly adjusted medication was ranitidine. Patients who required medication adjustment for renal dysfunction were significantly younger compared to those patients not requiring medication adjustment. Pharmacist recommendations were responsible for 96% of medication adjustments for renal dysfunction, and the recommendations were accepted and appropriate all of the time. The monetary impact of pharmacist interventions, in doses saved, was approximately $12,000. Pharmacist consultation can result in improved dosing of medications and cost savings. The youngest patients are most at risk for inappropriate dosing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.