ArticleMolecular genetics and genomics : MGG2008
Gac two-component system in Pseudomonas syringae pv. tabaci is required for virulence but not for hypersensitive reaction.
Article in Molecular genetics and genomics : MGG, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 52 citations in OpenAlex.
- TheApplied and environmental microbiology · 2026Article
- GacA reduces virulence and increases competitiveness in planta in the tumorigenic olive pathogenFrontiers in plant science · 2024Article
- Virulence-related regulatory network ofComputational and structural biotechnology journal · 2022Review
- Regulation of theMicroorganisms · 2021Review
- Review
- Transposon Insertion Sequencing in a Clinical Isolate of Legionella pneumophila Identifies Essential Genes and Determinants of Natural Transformation.Journal of bacteriology · 2021Article
- The Evanescent GacS Signal.Microorganisms · 2020Review
- A revised model for the role of GacS/GacA in regulating type III secretion by Pseudomonas syringae pv. tomato DC3000.Molecular plant pathology · 2020Article
- Transcriptomic Changes ofFrontiers in cellular and infection microbiology · 2019Article
- MexEF-OprN multidrug efflux pump transporter negatively controls N-acyl-homoserine lactone accumulation in pseudomonas syringae pv. Tabaci 6605.Molecular genetics and genomics : MGG · 2018Article
- The LetA/S two-component system regulates transcriptomic changes that are essential for the culturability of Legionella pneumophila in water.Scientific reports · 2018Article
- N-acylhomoserine lactone-regulation of genes mediating motility and pathogenicity in Pseudomonas syringae pathovar tabaci 11528.MicrobiologyOpen · 2017Article
- Regulation of bacterial virulence by Csr (Rsm) systems.Microbiology and molecular biology reviews : MMBR · 2015Review
- Characterization of quorum sensing-controlled transcriptional regulator MarR and Rieske (2Fe-2S) cluster-containing protein (Orf5), which are involved in resistance to environmental stresses in Pseudomonas syringae pv. tabaci 6605.Molecular plant pathology · 2015Article
- Roles of the Gac-Rsm pathway in the regulation of phenazine biosynthesis in Pseudomonas chlororaphis 30-84.MicrobiologyOpen · 2013Article
- Virulence factor regulator (Vfr) controls virulence-associated phenotypes in Pseudomonas syringae pv. tabaci 6605 by a quorum sensing-independent mechanism.Molecular plant pathology · 2013Article
- Characterization of each aefR and mexT mutant in Pseudomonas syringae pv. tabaci 6605.Molecular genetics and genomics : MGG · 2012Article
- The role of a periplasmic gluconolactonase (PpgL)-like protein in Pseudomonas syringae pv. syringae B728a.World journal of microbiology & biotechnology · 2011Article
- The siderophore pyoverdine of Pseudomonas syringae pv. tabaci 6605 is an intrinsic virulence factor in host tobacco infection.Journal of bacteriology · 2010Article
- Systems level analysis of two-component signal transduction systems in Erwinia amylovora: role in virulence, regulation of amylovoran biosynthesis and swarming motility.BMC genomics · 2009Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pseudomonas syringae pv. tabaci 6605 causes wildfire disease on host tobacco plants. To investigate the regulatory mechanism of the expression of virulence, Gac two-component system-defective mutants, DeltagacA and DeltagacS, and a double mutant, DeltagacADeltagacS, were generated. These mutants produced smaller amounts of N-acyl homoserine lactones required for quorum sensing, had lost swarming motility, and had reduced expression of virulence-related hrp genes and the algT gene required for exopolysaccharide production. The ability of the mutants to cause disease symptoms in their host tobacco plant was remarkably reduced, while they retained the ability to induce hypersensitive reaction (HR) in the nonhost plants. These results indicated that the Gac two-component system of P. syringae pv. tabaci 6605 is indispensable for virulence on the host plant, but not for HR induction in the nonhost plants.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.