ArticleVirchows Archiv : an international journal of pathology2008
Primary adrenocortical sarcomatoid carcinoma: case report and review of literature.
Article in Virchows Archiv : an international journal of pathology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Sarcomatoid adrenocortical carcinoma with aggressive disease course: a rare case report and literature review.Discover oncology · 2026Article
- A case of mineralocorticoid intermediate-producing sarcomatoid adrenal cortical carcinoma: case report and review of literature.Endocrine journal · 2025Review
- Adrenocortical Sarcomatoid Carcinoma Revealed by an Adrenal Incidentaloma: A Case Report.Cureus · 2024Article
- Insights into Clinical Features and Outcomes of Adrenal Cortical Carcinosarcoma.Diagnostics (Basel, Switzerland) · 2022Article
- Adrenal cancer: relevance of different grading systems and subtypes.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021Article
- Adrenocortical Carcinoma: Updates of Clinical and Pathological Features after Renewed World Health Organisation Classification and Pathology Staging.Biomedicines · 2021Review
- The challenge to differentiate between sarcoma or adrenal carcinoma-an observational study.Rare tumors · 2021Article
- Adrenocortical sarcomatoid carcinoma: a case report and review of the literature.Journal of surgical case reports · 2020Article
- Sarcomatoid Adrenal Carcinoma: Case Report with Contribution to Pathogenesis.Endocrine pathology · 2017Article
- Myxoid and Sarcomatoid Variants of Adrenocortical Carcinoma: Analysis of Rare Variants in Single Tertiary Care Center.Journal of Korean medical science · 2017Article
- Primary adrenal sarcomatoid carcinoma metastatic to the lung: Case report and review of the literature.Oncology letters · 2016Article
- A Case Report of Bilateral Adrenal Sarcomatoid Carcinoma.Case reports in surgery · 2016Article
- Diagnostic and prognostic features in adrenocortical carcinoma: a single institution case series and review of the literature.World journal of surgical oncology · 2015Review
- Rare incidence of primary adrenocortical carcinosarcoma: A case report and literature review.Oncology letters · 2015Article
- Adrenal sarcomatoid carcinoma: a case report and review of the literature.The Ulster medical journal · 2014Review
- Primary adrenal sarcomatoid carcinoma.Clinics and practice · 2014Article
- Pathology of the adrenal cortex: a reappraisal of the past 25 years focusing on adrenal cortical tumors.Endocrine pathology · 2014Article
- Adrenocortical neoplasia: evolving concepts in tumorigenesis with an emphasis on adrenal cortical carcinoma variants.Virchows Archiv : an international journal of pathology · 2012Review
- The Weiss score and beyond--histopathology for adrenocortical carcinoma.Hormones & cancer · 2011Review
- Adrenocortical carcinosarcoma: a case report and review of the literature.Diagnostic pathology · 2010Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adrenocortical carcinoma (AC) mixed with a sarcoma or sarcoma-like component is exceptional, and only six cases have been detailed in the literature, three including osteo-, chondro-, or rhabdomyosarcoma components, and three others only showing a malignant spindle cell component. These histological subtypes, respectively called adrenal carcinosarcomas and sarcomatoid AC, represent poorly differentiated and extremely aggressive forms of carcinoma, with locoregional recurrence and metastases rapidly arising from the sarcomatous or sarcomatoid component, and death occurring in a few months. We report a case of AC in a 31-year-old man presenting as a nonfunctional tumor, with a histological biphasic pattern combining few areas of differentiated AC and extensive areas of sarcomatoid spindle cell proliferation. The patient died 3 months of locoregional and distant recurrences after surgery despite apparently total tumor resection and VP16-cisplatinum chemotherapy. This case underlines the necessity to identify and isolate these carcinoma's subtypes with worse prognosis and the difficulties to distinguish them from metastatic carcinomas and retroperitoneal sarcomas, in relation to the particular adrenal cortex immunoprofile. According to the World Health Organization principles of terminology, we suggest these tumors be collectively classified as "adrenal sarcomatoid carcinomas," a designation that tends to unify all carcinomas with "pleomorphic, sarcomatoid, or sarcomatous elements."
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Registered trials
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