ArticleBlood2008
Gene alteration and precursor and mature microRNA transcription changes contribute to the miRNA signature of primary effusion lymphoma.
Article in Blood, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed.
- Systemically circulating viral and tumor-derived microRNAs in KSHV-associated malignancies.PLoS pathogens · 2013Trial
- Purification Methods and the Presence of RNA in Virus Particles and Extracellular Vesicles.Viruses · 2020Review
- Strategies to Modulate MicroRNA Functions for the Treatment of Cancer or Organ Injury.Pharmacological reviews · 2020Review
- Xeno-miRNA in Maternal-Infant Immune Crosstalk: An Aid to Disease Alleviation.Frontiers in immunology · 2020Review
- Epstein-Barr virus enhances genome maintenance of Kaposi sarcoma-associated herpesvirus.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Kaposi's Sarcoma-Associated Herpesvirus Latency Locus Renders B Cells Hyperresponsive to Secondary Infections.Journal of virology · 2018Article
- MicroRNA signatures and Foxp3Oncotarget · 2018Article
- Large-scale, cross-flow based isolation of highly pure and endocytosis-competent extracellular vesicles.Journal of extracellular vesicles · 2018Article
- Defining Plasma MicroRNAs Associated With Cognitive Impairment In HIV-Infected Patients.Journal of cellular physiology · 2016Article
- MicroRNA expression profiles of bovine milk exosomes in response to Staphylococcus aureus infection.BMC genomics · 2015Article
- MicroRNAs regulate bone development and regeneration.International journal of molecular sciences · 2015Review
- Review
- Interleukin 1 receptor-associated kinase 1 (IRAK1) mutation is a common, essential driver for Kaposi sarcoma herpesvirus lymphoma.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Review
- A positive role of microRNA-15b on regulation of osteoblast differentiation.Journal of cellular physiology · 2014Article
- Viral microRNA genomics and target validation.Current opinion in virology · 2014Review
- Serum microRNAs in HIV-infected individuals as pre-diagnosis biomarkers for AIDS-NHL.Journal of acquired immune deficiency syndromes (1999) · 2014Article
- Toll-like receptor-3 is dispensable for the innate microRNA response to West Nile virus (WNV).PloS one · 2014Article
- Latency locus complements MicroRNA 155 deficiency in vivo.Journal of virology · 2013Article
- Kaposi's sarcoma-associated herpesvirus microRNA single-nucleotide polymorphisms identified in clinical samples can affect microRNA processing, level of expression, and silencing activity.Journal of virology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
MicroRNAs are regulated by gene alteration, transcription, and processing. Thus far, few studies have simultaneously assessed all 3 levels of regulation. Using real-time quantitative polymerase chain reaction (QPCR)-based arrays, we determined changes in gene copy number, pre-miRNA, and mature miRNA levels for the largest set of primary effusion lymphomas (PELs) to date. We detected PEL-specific miRNA gene amplifications, and concordant changes in pre-miRNA and mature miRNA. We identified 68 PEL-specific miRNAs. This defines the miRNA signature of PEL and shows that transcriptional regulation of pre-miRNA as well as mature miRNA levels contribute nonredundant information that can be used for the classification of human tumors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.