ReviewHeart failure reviews2008
Noninvasive imaging of apoptosis in cardiovascular disease.
Review in Heart failure reviews, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 54 citations in OpenAlex.
- Infiltrative and Inflammatory Cardiomyopathies: Using Imaging to Probe Mechanisms of Myocardial Dysfunction.Journal of cardiac failure · 2026Review
- Estrone-salicylaldehyde N-methylated thiosemicarbazone hybrids and their copper complexes: solution structure, stability and anticancer activity in tumour spheroids.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2021Article
- Therapeutic Potential of Annexins in Sepsis and COVID-19.Frontiers in pharmacology · 2021Review
- Radiolabeled Duramycin: Promising Translational Imaging of Myocardial Apoptosis.JACC. Cardiovascular imaging · 2018Article
- Searching for novel PET radiotracers: imaging cardiac perfusion, metabolism and inflammation.American journal of nuclear medicine and molecular imaging · 2018Review
- PET-CMR in heart failure - synergistic or redundant imaging?Heart failure reviews · 2017Review
- Radionuclide Imaging Applications in Cardiomyopathies and Heart Failure.Current cardiology reports · 2016Review
- Correlation between apoptosis and left ventricular remodeling in subacute phase of myocardial ischemia and reperfusion.EJNMMI research · 2015Article
- Noninvasive imaging of cardiovascular injury related to the treatment of cancer.JACC. Cardiovascular imaging · 2014Review
- Beyond annexin V: fluorescence response of cellular membranes to apoptosis.Cytotechnology · 2013Article
- Protective effect of the apoptosis-sensing nanoparticle AnxCLIO-Cy5.5.Nanomedicine : nanotechnology, biology, and medicine · 2012Article
- From molecules to myofibers: multiscale imaging of the myocardium.Journal of cardiovascular translational research · 2011Review
- Protease probes built from DNA: multispectral fluorescent DNA-peptide conjugates as caspase chemosensors.Angewandte Chemie (International ed. in English) · 2011Article
- Measurement of the binding parameters of annexin derivative-erythrocyte membrane interactions.Analytical biochemistry · 2010Article
- Small-animal SPECT and SPECT/CT: application in cardiovascular research.European journal of nuclear medicine and molecular imaging · 2010Review
- An approach to molecular imaging of atherosclerosis, thrombosis, and vascular inflammation using microparticles of iron oxide.Atherosclerosis · 2010Review
- Long-term luciferase expression monitored by bioluminescence imaging after adeno-associated virus-mediated fetal gene delivery in rhesus monkeys (Macaca mulatta).Human gene therapy · 2010Article
- Molecular MRI detects low levels of cardiomyocyte apoptosis in a transgenic model of chronic heart failure.Circulation. Cardiovascular imaging · 2009Article
- A DNA-binding Gd chelate for the detection of cell death by MRI.Chemical communications (Cambridge, England) · 2009Article
- Molecular Imaging of Myocardial Injury: A Magnetofluorescent Approach.Current cardiovascular imaging reports · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Recent advances in molecular imaging have permitted the noninvasive imaging of apoptosis, a critical process underlying the pathogenesis of many diseases of the cardiovascular system including atherosclerotic vascular disease, myocardial ischemia and reperfusion injury, chronic heart failure, myocarditis, and cardiac allograft rejection. Multiple molecular targets including phosphatidylserine, phosphatidylinositol 3-kinase, and caspases have been targeted by a variety of imaging agents and modalities such as nuclear scintigraphy, PET, MRI, and fluorescent and bioluminescent imaging. Translationally, methods utilizing radiolabeled annexin V have proven promising in several clinical trials of ischemia-reperfusion injury and cardiac allograft rejection. New approaches using novel molecular imaging agents show great potential for the ability to image apoptosis in the research and clinical setting. Ultimately the ability to detect apoptosis noninvasively would help to identify patients for emerging anti-apoptotic therapies and guide clinical management with the aim of maximal myocardial preservation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.