ReviewObesity surgery2008
Effects of weight loss on bone status after bariatric surgery: association between adipokines and bone markers.
Review in Obesity surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02893891 (Metabolic Changes of Fat and Bone Tissue After Radical Bariatric Surgery), which is not on this map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Metabolic Changes of Fat and Bone Tissue After Radical Bariatric Surgery
Who cites it
29 citing papers in PubMed, 62 citations in OpenAlex.
- Effects of high-intensity resistance training on extended body composition and functional fitness after spinal cord injury with motor complete paraplegia: a randomized controlled trial study.Frontiers in public health · 2025Trial
- Intestinal Calcium Absorption Decreases Dramatically After Gastric Bypass Surgery Despite Optimization of Vitamin D Status.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2015Trial
- Increase of osteopontin plasma concentrations after bariatric surgery independent from inflammation and insulin resistance.Obesity surgery · 2009Trial
- Changes in bone mineral density, body composition and adiponectin levels in morbidly obese patients after bariatric surgery.Obesity surgery · 2009Trial
- The PYY/Y2R-deficient male mouse is not protected from bone loss due to Roux-en-Y gastric bypass.Bone · 2023Article
- Effects of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy on Bone Mineral Density in Zucker Diabetic Fatty Rats: A Short-Term Comparative Study.Obesity facts · 2021Article
- Barocrinology: The Endocrinology of Obesity from Bench to Bedside.Medical sciences (Basel, Switzerland) · 2020Review
- Bariatric Surgery: Remission of Inflammation, Cardiometabolic Benefits, and Common Adverse Effects.Journal of the Endocrine Society · 2020Review
- Association of Bariatric Surgery With Risk of Fracture in Patients With Severe Obesity.JAMA network open · 2020Article
- Determining changes in bone metabolism after bariatric surgery in postmenopausal women.Surgical endoscopy · 2020Article
- Metabolic and Endocrine Consequences of Bariatric Surgery.Frontiers in endocrinology · 2019Review
- Thin bones: Vitamin D and calcium handling after bariatric surgery.Bone reports · 2018Article
- Article
- Cardiovascular effects of bariatric surgery.Nature reviews. Cardiology · 2016Review
- Indications for Surgery for Obesity and Weight-Related Diseases: Position Statements from the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO).Obesity surgery · 2016Article
- Effects of omega-loop gastric bypass on vitamin D and bone metabolism in morbidly obese bariatric patients.Obesity surgery · 2015Article
- Bone metabolism after bariatric surgery.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2014Review
- Changes in bone mineral density after sleeve gastrectomy or gastric bypass: relationships with variations in vitamin D, ghrelin, and adiponectin levels.Obesity surgery · 2014Article
- Short- and mid-term changes in bone mineral density after laparoscopic sleeve gastrectomy.Obesity surgery · 2013Observational
- The prolonged survival of fibroblasts with forced lipid catabolism in visceral fat following encapsulation in alginate-poly-L-lysine.Biomaterials · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of overweight and obesity is increasing dramatically worldwide. As a consequence, bariatric surgery for morbid obesity is in constant development. Although bariatric surgery has proven its efficiency at achieving weight loss and correcting comorbidities, it may cause vitamin deficiencies and subsequent complications. The goal of this review is to assess the impact of obesity surgery on bone metabolism and to analyze the underlying mechanisms and relationships with adipokines. Our review focuses on gastric banding, vertical banded gastroplasty, and gastric bypass.
methodsThe articles were located via PubMed database, using the key words "bariatric surgery," "weight loss," "bone loss," and "bone metabolism" and published until May 2006.
resultsFive main studies were reviewed concerning gastric banding and six concerning Roux-en-Y gastric bypass. An early increase in bone markers (formation and resorption) is constantly found, prevailing on bone resorption, and resulting in early bone loss.
conclusionAccording to the few studies available, bone loss frequently occurs after bariatric surgery and particularly in a more pronounced way after gastric bypass, but its clinical significance is still under discussion. In addition, the physiopathology of these changes remains unclear, but could implicate adipokines such as leptin and adiponectin.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.