ArticleGenetics2007
Subtelomeric elements influence but do not determine silencing levels at Saccharomyces cerevisiae telomeres.
Article in Genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 33 citations in OpenAlex.
- Systematic profiling of subtelomeric silencing factors in budding yeast.G3 (Bethesda, Md.) · 2023Article
- Transcription termination complex, Rtt103-Rai1-Rat1, regulates sub-telomeric transcripts inRNA biology · 2023Article
- In vivo chromatin organization on native yeast telomeric regions is independent of a cis-telomere loopback conformation.Epigenetics & chromatin · 2020Article
- Yeast mismatch repair components are required for stable inheritance of gene silencing.PLoS genetics · 2020Article
- A subtelomeric region affects telomerase-negative replicative senescence in Saccharomyces cerevisiae.Scientific reports · 2019Article
- Article
- Silencing is noisy: population and cell level noise in telomere-adjacent genes is dependent on telomere position and sir2.PLoS genetics · 2014Article
- Article
- Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end.Genetics · 2012Review
- The tail-module of yeast Mediator complex is required for telomere heterochromatin maintenance.Nucleic acids research · 2012Article
- Regulating repression: roles for the sir4 N-terminus in linker DNA protection and stabilization of epigenetic states.PLoS genetics · 2012Article
- Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms.Epigenetics & chromatin · 2011Article
- Telomere position effect is regulated by heterochromatin-associated proteins and NkuA in Aspergillus nidulans.Microbiology (Reading, England) · 2010Article
- An auxiliary silencer and a boundary element maintain high levels of silencing proteins at HMR in Saccharomyces cerevisiae.Genetics · 2010Article
- Positional dependence of transcriptional inhibition by DNA torsional stress in yeast chromosomes.The EMBO journal · 2010Article
- Silent information regulator 3: the Goldilocks of the silencing complex.Genes & development · 2010Review
- Distinct differences in chromatin structure at subtelomeric X and Y' elements in budding yeast.PloS one · 2009Article
- A silencer promotes the assembly of silenced chromatin independently of recruitment.Molecular and cellular biology · 2009Article
- yKu70/yKu80 and Rif1 regulate silencing differentially at telomeres in Candida glabrata.Eukaryotic cell · 2008Article
- The DNA end-binding protein Ku regulates silencing at the internal HML and HMR loci in Saccharomyces cerevisiae.Genetics · 2008Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Saccharomyces cerevisiae, genes placed near telomeres are transcriptionally repressed (telomere position effect, TPE). Although telomeric DNA sequence is the same at all chromosome ends, the subtelomeric elements (STEs) and level of TPE vary from telomere to telomere. We tested whether STEs determine TPE levels. STEs contributed to TPE, as deleting the X element from the VI-R telomere modestly decreased silencing at this telomere. However, STEs were not the major determinant of TPE levels, as inserting the VI-R X element at the truncated VII-L telomere did not increase TPE. These data suggest that the TPE levels of individual telomeres are dependent on some aspect of chromosome context.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.