ArticleGenetics2007
Investigation of the demographic and selective forces shaping the nucleotide diversity of genes involved in nod factor signaling in Medicago truncatula.
Article in Genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 44 citations in OpenAlex.
- Effect of different Bradyrhizobium japonicum inoculants on physiological and agronomic traits of soybean (Glycine max (L.) Merr.) associated with different expression of nodulation genes.BMC plant biology · 2024Article
- Evolution of flowering time in a selfing annual plant: Roles of adaptation and genetic drift.Ecology and evolution · 2022Article
- Comparative genomics reveals high rates of horizontal transfer and strong purifying selection on rhizobial symbiosis genes.Proceedings. Biological sciences · 2021Article
- Evolutionary History of Plant LysM Receptor Proteins Related to Root Endosymbiosis.Frontiers in plant science · 2018Article
- Standing genetic variation in host preference for mutualist microbial symbionts.Proceedings. Biological sciences · 2014Article
- Mapping the genetic basis of symbiotic variation in legume-rhizobium interactions in Medicago truncatula.G3 (Bethesda, Md.) · 2012Article
- Impact of sampling schemes on demographic inference: an empirical study in two species with different mating systems and demographic histories.G3 (Bethesda, Md.) · 2012Article
- Article
- Whole-genome nucleotide diversity, recombination, and linkage disequilibrium in the model legume Medicago truncatula.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Molecular adaptation in flowering and symbiotic recognition pathways: insights from patterns of polymorphism in the legume Medicago truncatula.BMC evolutionary biology · 2011Article
- SNiPlay: a web-based tool for detection, management and analysis of SNPs. Application to grapevine diversity projects.BMC bioinformatics · 2011Article
- High amino acid diversity and positive selection at a putative coral immunity gene (tachylectin-2).BMC evolutionary biology · 2010Article
- Gene conversion and positive selection driving the evolution of the Caenorhabditis ssp. ZIM/HIM-8 protein family.Journal of molecular evolution · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Symbiotic nitrogen-fixing rhizobia are able to trigger root deformation in their Fabaceae host plants, allowing their intracellular accommodation. They do so by delivering molecules called Nod factors. We analyzed the patterns of nucleotide polymorphism of five genes controlling early Nod factor perception and signaling in the Fabaceae Medicago truncatula to understand the selective forces shaping the evolution of these genes. We used 30 M. truncatula genotypes sampled in a genetically homogeneous region of the species distribution range. We first sequenced 24 independent loci and detected a genomewide departure from the hypothesis of neutrality and demographic equilibrium that suggests a population expansion. These data were used to estimate parameters of a simple demographic model incorporating population expansion. The selective neutrality of genes controlling Nod factor perception was then examined using a combination of two complementary neutrality tests, Tajima's D and Fay and Wu's standardized H. The joint distribution of D and H expected under neutrality was obtained under the fitted population expansion model. Only the gene DMI1, which is expected to regulate the downstream signal, shows a pattern consistent with a putative selective event. In contrast, the receptor-encoding genes NFP and NORK show no significant signatures of selection. Among the genes that we analyzed, only DMI1 should be viewed as a candidate for adaptation in the recent history of M. truncatula.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.