Evidence map›Paper›PMID 18071578›Full record

ArticleComparative biochemistry and physiology. Part D, Genomics & proteomics2007

Fundulus as the premier teleost model in environmental biology: opportunities for new insights using genomics.

Karen G Burnett, Lisa J Bain, William S Baldwin, Gloria V Callard, Sarah Cohen, Richard T Di Giulio, David H Evans, Marta Gómez-Chiarri, Mark E Hahn, Cindi A Hoover and 16 more

Abstract read
In one paragraph

Article in Comparative biochemistry and physiology. Part D, Genomics & proteomics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Effects of 17α-Ethinylestradiol on Development and Gonadal Differentiation in the Estuarine Mummichog, Fundulus heteroclitus.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Complete mitochondrial genome of the Starhead TopminnowMitochondrial DNA. Part B, Resources · 2024
    Article
  9. Article
  10. Article
  11. A novel gnotobiotic experimental system for Atlantic salmon (Frontiers in cellular and infection microbiology · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Long-Term Ecological Impacts from Oil Spills: Comparison ofEnvironmental science & technology · 2020
    Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Karen G BurnettGrice Marine Laboratory, College of Charleston, 205 Fort Johnson, Charleston, SC 29412, USA.
Lisa J Bain
William S Baldwin
Gloria V Callard
Sarah Cohen
Richard T Di Giulio
David H Evans
Marta Gómez-Chiarri
Mark E Hahn
Cindi A Hoover
Sibel I Karchner
Fumi Katoh
Deborah L Maclatchy
William S Marshall
Joel N Meyer
Diane E Nacci
Marjorie F Oleksiak
Bernard B Rees
Thomas D Singer
John J Stegeman
David W Towle
Peter A Van Veld
Wolfgang K Vogelbein
Andrew Whitehead
Richard N Winn
Douglas L Crawford

Funding

Zebrafish as a Detector of Organophosphate ExposureP42ES010356 · NIEHS · DUKE UNIVERSITY · PI AMY H HERRING · 2000 to 2026
$56.2M
Training CoreP42ES007381 · NIEHS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SHERR, DAVID H · 1995 to 2019
$46.1M
WNT SIGNALING IN THE DEVELOPING GASTROINTESTINAL TRACTP20RR016463 · NCRR · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI HAND, PATRICIA H. · 2001 to 2011
$41.0M
UTEP SCORE InstrumentationS06GM008012 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI ALMEIDA, IGOR C · 1989 to 2010
$15.8M
Microarray Analyses of Polluted Natural PopulationsR01ES011588 · NIEHS · UNIVERSITY OF MIAMI ROSENTEIL SCHOOL · PI OLEKSIAK, MARJORIE F · 2004 to 2008
$1.5M
NCRR NIH HHS P20 RR016463NIEHS NIH HHS P42 ES007381NIEHS NIH HHS P42 ES010356NIEHS NIH HHS R01 ES011588
6 · The paper itself

Abstract

A strong foundation of basic and applied research documents that the estuarine fish Fundulus heteroclitus and related species are unique laboratory and field models for understanding how individuals and populations interact with their environment. In this paper we summarize an extensive body of work examining the adaptive responses of Fundulus species to environmental conditions, and describe how this research has contributed importantly to our understanding of physiology, gene regulation, toxicology, and ecological and evolutionary genetics of teleosts and other vertebrates. These explorations have reached a critical juncture at which advancement is hindered by the lack of genomic resources for these species. We suggest that a more complete genomics toolbox for F. heteroclitus and related species will permit researchers to exploit the power of this model organism to rapidly advance our understanding of fundamental biological and pathological mechanisms among vertebrates, as well as ecological strategies and evolutionary processes common to all living organisms.

Indexed as

ecological genomicsenvironmental genomicsevolutionary genomicsFundulus heteroclitusphysiological genomicstoxicogenomics

Identifiers

PMID18071578
PMCPMC2128618

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.