Evidence map›Paper›PMID 18070963›Full record

ArticleAntimicrobial agents and chemotherapy2008

Tetracycline resistance gene tet(W) in the pathogenic bacterium Clostridium difficile.

Patrizia Spigaglia, Fabrizio Barbanti, Paola Mastrantonio

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 51 citations in OpenAlex.

  1. Clostridioides difficile pathogenesis and control.Nature reviews. Microbiology · 2026
    Review
  2. Clinical microbiology reviews · 2024
    Review
  3. Article
  4. Antibiotic Resistances of Clostridioides difficile.Advances in experimental medicine and biology · 2024
    Article
  5. Article
  6. Mechanisms of antibiotic resistance of Clostridioides difficile.The Journal of antimicrobial chemotherapy · 2021
    Review
  7. Microorganisms · 2021
    Review
  8. The Tetracycline Resistance Gene,Frontiers in microbiology · 2021
    Article
  9. Occurrence ofMicroorganisms · 2020
    Article
  10. Antimicrobial Resistance inMicrobiology spectrum · 2020
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Genome Analysis ofFrontiers in microbiology · 2016
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Patrizia SpigagliaDepartment of Infectious, Parasitic and Immune-mediated Diseases, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Fabrizio Barbanti
Paola Mastrantonio
Istituto Superiore di Sanità · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, the tet(W) gene region of a human clinical isolate of Clostridium difficile resistant to tetracycline was characterized. This gene was a new allele showing 99% sequence identity to the gene found in the human strain Bifidobacterium longum F8, and it is not transferable by "in vitro" mating experiments.

Indexed as

Anti-Bacterial AgentsBacterial ProteinsChild, PreschoolClostridioides difficileDNA, BacterialEnterocolitis, PseudomembranousHumansMicrobial Sensitivity TestsMolecular Sequence DataPhylogenySequence Analysis, DNATetracyclineTetracycline ResistanceAnti-Bacterial AgentsBacterial ProteinsDNA, BacterialTetracycline

Identifiers

PMID18070963
PMCPMC2224778
OpenAlexW2126626130

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.