ArticleBMC genomics2007
Variable sexually dimorphic gene expression in laboratory strains of Drosophila melanogaster.
Article in BMC genomics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Dissecting the Transcriptional Patterns of Social Dominance across Teleosts.Integrative and comparative biology · 2016Pooled it
- Dicodon-based measures for modeling gene expression.Bioinformatics (Oxford, England) · 2023Article
- Differential Expression ofFrontiers in cell and developmental biology · 2021Article
- Article
- Mating system manipulation and the evolution of sex-biased gene expression in Drosophila.Nature communications · 2017Article
- Mating Changes Sexually Dimorphic Gene Expression in the Seed Beetle Callosobruchus maculatus.Genome biology and evolution · 2017Article
- From sexless to sexy: Why it is time for human genetics to consider and report analyses of sex.Biology of sex differences · 2017Article
- Bidirectional promoters of insects: genome-wide comparison, evolutionary implication and influence on gene expression.Journal of molecular biology · 2015Article
- The effect of epistasis on sexually antagonistic genetic variation.Proceedings. Biological sciences · 2014Article
- Article
- Genomics of sex determination in Drosophila.Briefings in functional genomics · 2012Article
- Identification, expression and target gene analyses of Micrornas in Spodoptera litura.PloS one · 2012Article
- Population transcriptomics of Drosophila melanogaster females.BMC genomics · 2011Article
- Neighbourhood continuity is not required for correct testis gene expression in Drosophila.PLoS biology · 2010Article
- Insights into the role of differential gene expression on the ecological adaptation of the snail Littorina saxatilis.BMC evolutionary biology · 2010Article
- The transcriptional response of Drosophila melanogaster to infection with the sigma virus (Rhabdoviridae).PloS one · 2009Article
- Article
- Are sex-biased genes more dispensable?Biology letters · 2009Article
- Gene expression during Drosophila melanogaster egg development before and after reproductive diapause.BMC genomics · 2009Article
- Sex-specific genetic architecture of human disease.Nature reviews. Genetics · 2008Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundWild-type laboratory strains of model organisms are typically kept in isolation for many years, with the action of genetic drift and selection on mutational variation causing lineages to diverge with time. Natural populations from which such strains are established, show that gender-specific interactions in particular drive many aspects of sequence level and transcriptional level variation. Here, our goal was to identify genes that display transcriptional variation between laboratory strains of Drosophila melanogaster, and to explore evidence of gender-biased interactions underlying that variability.
resultsTranscriptional variation among the laboratory genotypes studied occurs more frequently in males than in females. Qualitative differences are also apparent to suggest that genes within particular functional classes disproportionately display variation in gene expression. Our analysis indicates that genes with reproductive functions are most often divergent between genotypes in both sexes, however a large proportion of female variation can also be attributed to genes without expression in the ovaries.
conclusionThe present study clearly shows that transcriptional variation between common laboratory strains of Drosophila can differ dramatically due to sexual dimorphism. Much of this variation reflects sex-specific challenges associated with divergent physiological trade-offs, morphology and regulatory pathways operating within males and females.
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