Evidence map›Paper›PMID 18070148›Full record

ReviewClinical and experimental immunology2008

Translational mini-review series on complement factor H: therapies of renal diseases associated with complement factor H abnormalities: atypical haemolytic uraemic syndrome and membranoproliferative glomerulonephritis.

M Noris, G Remuzzi

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical and experimental immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Complement inhibitor eculizumab in atypical hemolytic uremic syndrome.Clinical journal of the American Society of Nephrology : CJASN · 2009
    Article
  9. Article
  10. Complement and the atypical hemolytic uremic syndrome in children.Pediatric nephrology (Berlin, Germany) · 2008
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

M NorisClinical Research Center for Rare Diseases Aldo e Cele Daccò, Mario Negri Institute for Pharmacological Research, Villa Camozzi - Ranica (BG), Italy. noris@marionegri.it
G Remuzzi
Mario Negri Institute for Pharmacological Research · IT

Funding

International Network and Registry for TMAR21DK071221 · NIDDK · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI TRACHTMAN, HOWARD · 2006 to 2007
$405k
NIDDK NIH HHS DK71221NIDDK NIH HHS R21 DK071221
6 · The paper itself

Abstract

Genetic and acquired abnormalities in complement factor H (CFH) have been associated with two different human renal diseases: haemolytic uraemic syndrome and membrano proliferative glomerulonephritis. The new genetic and pathogenetic findings in these diseases and their clinical implications for the management and cure of patients are reviewed in this paper.

Indexed as

Complement Factor HGlomerulonephritis, MembranoproliferativeHemolytic-Uremic SyndromeHumansCFH protein, humanComplement Factor H

Identifiers

PMID18070148
PMCPMC2276938
OpenAlexW1522781629

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.