ReviewAnnals of hematology2008
Iron and thrombosis.
Review in Annals of hematology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02809274 (Incidence of Iron Deficiency in Polycythemia Vera), which is not on this map. Cited by 65 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Incidence of Iron Deficiency in Polycythemia Vera (PV) and Association With Disease Features
Who cites it
65 citing papers in PubMed, 4 syntheses or guidelines pooled it, 136 citations in OpenAlex.
- Mendelian randomization studies on ischemic stroke: a field synopsis and systematic review.Journal of translational medicine · 2025Pooled it
- Guideline
- Systemic inflammation in COVID-19 patients may induce various types of venous and arterial thrombosis: A systematic review.Scandinavian journal of immunology · 2021Pooled it
- Iron deficiency and cardiovascular disease: an updated review of the evidence.Current atherosclerosis reports · 2013Pooled it
- Hydroxytyrosol supplementation increases vitamin C levels in vivo. A human volunteer trial.Redox biology · 2017Trial
- The relationship of initial transferrin saturation to cardiovascular parameters and outcomes in patients initiating dialysis.PloS one · 2014Trial
- Utility of rotational thrombo-elastometry as an objective measure of hypercoagulability in ulcerative colitis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Article
- The effect of parenteral iron treatment on ocular vascularity in female patients with iron deficiency anemia.International ophthalmology · 2026Observational
- Anemia as a Potent and Underrecognized Driver of Venous Thromboembolism: A Systematic Review.Journal of clinical medicine · 2026Review
- Isolated Ulnar Artery Occlusion with Concurrent Internal Jugular Vein Thrombosis in Severe Iron-Deficiency Anaemia.European journal of case reports in internal medicine · 2026Article
- Evaluation of Serum Iron and Platelet Parameters in Dogs.Animals : an open access journal from MDPI · 2025Article
- Emerging Trends in Patients Hospitalised With Cirrhosis-Aetiologies, Complications and Outcomes Compared to Other Chronic Health Conditions.Alimentary pharmacology & therapeutics · 2025Article
- Endothelial cell iron overload and ferroptosis mediate thrombosis and inflammation through the miR-32-5p/neurofibromin 2 pathway.European journal of medical research · 2025Article
- Pulmonary Embolism: Highlighting Iron Deficiency Anemia as a Contributing Factor in the Development of Pulmonary Embolism-A Case Report.Clinical case reports · 2025Article
- Resolving the developmental mechanisms of cardiac microthrombosis of SARS-CoV-2 based on single-cell transcriptome analysis.Science China. Life sciences · 2025Article
- Case Report: Cerebral venous sinus thrombosis in the setting of iron deficiency anemia and a high level of lipoprotein (a) in a child.Frontiers in pediatrics · 2025Article
- Navigating anemia and anticoagulation in elderly patients undergoing orthopedic surgery: strategies for preventing complications and implementing treatments.Blood transfusion = Trasfusione del sangue · 2024Review
- Polygenic Risk Score-Based Association Analysis Identifies Genetic Comorbidities Associated with Age-Related Hearing Difficulty in Two Independent Samples.Journal of the Association for Research in Otolaryngology : JARO · 2024Article
- Pure Tone Audiometry in Anemia Patients.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Can iron chelators ameliorate viral infections?Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024Review
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although essential for cell physiology, an increase or depletion of body iron has harmful effects on health. Apart from iron deficiency anemia and iron overload-related organ tissue damage, there are increasing evidences that body iron status is implicated in atherosclerotic cardiovascular diseases. The hypothesis formulated in 1981 that iron depletion may protect against cardiovascular events is intriguing and has generated a significant debate in the last two decades. Indeed, to study this phenomenon, several investigators have tried to design appropriate experimental and clinical studies and to identify useful biochemical and genetic markers of iron status. The results of the literature on the effect of iron deficiency and overload on vascular health are critically reviewed in this study from a pathogenic and clinical point of view.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.