Evidence map›Paper›PMID 18066507›Full record

ArticleDer Anaesthesist2008

[Metabolic alkalosis despite hyperlactatemia and hypercapnia. Interpretation and therapy with help of the Stewart concept].

D Chappell, K Hofmann-Kiefer, M Jacob, P Conzen, M Rehm

Abstract readCase ReportsEnglish Abstract
PubMed Publisher
In one paragraph

Article in Der Anaesthesist, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. [Acid-base concepts].Der Anaesthesist · 2009
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

D ChappellKlinik für Anästhesiologie, Universitätsklinikum der Ludwig-Maximilians Universität, Nussbaumstrasse 20, 80336 München.
K Hofmann-Kiefer
M Jacob
P Conzen
M Rehm

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acid-base disturbances are commonly found in critically ill patients and are often associated with fatal complications. The basis of a successful treatment is a thorough understanding of the causes of these disorders. The "classical methods" to explain acid-base disorders--pH, base excess and bicarbonate concentration--mostly do not provide a causal correlation to the underlying pathology. An unusual case of a combined respiratory-metabolic disorder with hyperlactatemia and hypercapnia is presented. An acidosis masked by hypochloremic and hypoalbuminemic alkalosis was identified with the help of Stewart's concept and finally permitted a successful therapy. The modern Stewart concept provides enhanced information, enabling an exact diagnosis and causal therapy even in complex cases.

Indexed as

Acid-Base EquilibriumAcidosisAgedAlkalosisBlood Gas AnalysisChloridesCritical CareHumansHydrogen-Ion ConcentrationHypercapniaHypoalbuminemiaLactatesMaleModels, StatisticalChloridesLactates

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.