ArticleApplied and environmental microbiology2008
First detection of mycobacteria in African rodents and insectivores, using stratified pool screening.
Article in Applied and environmental microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 63 citations in OpenAlex.
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- The Presence ofMicroorganisms · 2022Article
- Community-based geographical distribution of Mycobacterium ulcerans VNTR-genotypes from the environment and humans in the Nyong valley, Cameroon.Tropical medicine and health · 2021Article
- Risk Management in the New Frontier of Professional Liability for Nosocomial Infection: Review of the Literature on Mycobacterium Chimaera.International journal of environmental research and public health · 2020Review
- Article
- Domestic animals infected with Mycobacterium ulcerans-Implications for transmission to humans.PLoS neglected tropical diseases · 2018Article
- Bias Correction in Estimating Proportions by Pooled Testing.Journal of agricultural, biological, and environmental statistics · 2017Article
- Mycobacterium arupense in Cancer Patients: An Emerging Infection or a Commensal Organism.Medicine · 2016Article
- Source tracking Mycobacterium ulcerans infections in the Ashanti region, Ghana.PLoS neglected tropical diseases · 2015Article
- Investigating the role of free-living amoebae as a reservoir for Mycobacterium ulcerans.PLoS neglected tropical diseases · 2014Article
- Prevalence of bovine tuberculosis in slaughtered cattle identified by nested-PCR in abattoirs from two dairy areas of Ecuador.Tropical animal health and production · 2014Article
- Mycobacterium arupense flexor tenosynovitis: case report and review of antimicrobial susceptibility profiles for 40 clinical isolates.Journal of clinical microbiology · 2014Review
- Clinical, microbiological and pathological findings of Mycobacterium ulcerans infection in three Australian Possum species.PLoS neglected tropical diseases · 2014Article
- Assessment of three mitochondrial genes (16S, Cytb, CO1) for identifying species in the Praomyini tribe (Rodentia: Muridae).PloS one · 2012Article
- Buruli-ulcer induced disability in ghana: a study at apromase in the ashanti region.Plastic surgery international · 2012Article
- Mycobacteria in terrestrial small mammals on cattle farms in Tanzania.Veterinary medicine international · 2011Article
- Terrestrial small mammals as reservoirs of Mycobacterium ulcerans in benin.Applied and environmental microbiology · 2010Article
- The prevalence of Mycobacterium bovis-infection and atypical mycobacterioses in cattle in and around Morogoro, Tanzania.Tropical animal health and production · 2009Article
- Occurrence of free-living amoebae in communities of low and high endemicity for Buruli ulcer in southern Benin.Applied and environmental microbiology · 2008Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With the rising number of patients with human immunodeficiency virus (HIV)/AIDS in developing countries, the control of mycobacteria is of growing importance. Previous studies have shown that rodents and insectivores are carriers of mycobacteria. However, it is not clear how widespread mycobacteria are in these animals and what their role is in spreading them. Therefore, the prevalence of mycobacteria in rodents and insectivores was studied in and around Morogoro, Tanzania. Live rodents were trapped, with three types of live traps, in three habitats. Pieces of organs were pooled per habitat, species, and organ type (stratified pooling); these sample pools were examined for the presence of mycobacteria by PCR, microscopy, and culture methods. The mycobacterial isolates were identified using phenotypic techniques and sequencing. In total, 708 small mammals were collected, 31 of which were shrews. By pool prevalence estimation, 2.65% of the animals were carriers of mycobacteria, with a higher prevalence in the urban areas and in Cricetomys gambianus and the insectivore Crocidura hirta. Nontuberculous mycobacteria (Mycobacterium chimaera, M. intracellulare, M. arupense, M. parascrofulaceum, and Mycobacterium spp.) were isolated from C. gambianus, Mastomys natalensis, and C. hirta. This study is the first to report findings of mycobacteria in African rodents and insectivores and the first in mycobacterial ecology to estimate the prevalence of mycobacteria after stratified pool screening. The fact that small mammals in urban areas carry more mycobacteria than those in the fields and that potentially pathogenic mycobacteria were isolated identifies a risk for other animals and humans, especially HIV/AIDS patients, that have a weakened immune system.
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