ArticleJournal of bacteriology2008
Ma-LMM01 infecting toxic Microcystis aeruginosa illuminates diverse cyanophage genome strategies.
Article in Journal of bacteriology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
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Who cites it
70 citing papers in PubMed, 131 citations in OpenAlex.
- Acclimation temperature influences phage susceptibility in a toxin-producing strain ofMicrobiology spectrum · 2026Article
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- Virus Infection of a Freshwater Cyanobacterium Contributes Significantly to the Release of Toxins Through Cell Lysis.Microorganisms · 2025Article
- Lysogen formation governs colonies while lytic infection is more prevalent in single cells of the bloom-forming cyanobacterium,bioRxiv : the preprint server for biology · 2025Article
- Contrasting viral infection strategies for single cell and colonial Microcystis populations consistent with Black Queen dynamics.The ISME journal · 2025Article
- Cyanobacteriochrome-like GAF folds in phages revealed via AlphaFold proteomic modelling.Computational and structural biotechnology journal · 2025Article
- Cyanophage Engineering for Algal Blooms Control.Viruses · 2024Review
- Structural models predict a significantly higher binding affinity between the NblA protein of cyanophage Ma-LMM01 and the phycocyanin ofVirus evolution · 2024Article
- The Impact of Viral Infection on the Chemistries of the Earth's Most Abundant Photosynthesizes: Metabolically Talented Aquatic Cyanobacteria.Biomolecules · 2023Article
- Corrected and Republished from: "Isolation and Characterization of the First Freshwater Cyanophage InfectingJournal of virology · 2023Article
- Genomic Analysis of a New Freshwater Cyanophage Lbo240-yong1 Suggests a New Taxonomic Family of Bacteriophages.Viruses · 2023Article
- Biological and Genomic Characteristics of MaMV-DH01, a Novel FreshwaterMicrobiology spectrum · 2023Article
- Phylogenomics of five Pseudanabaena cyanophages and evolutionary traces of horizontal gene transfer.Environmental microbiome · 2023Article
- Multi-year molecular quantification and 'omics analysis ofFrontiers in microbiology · 2023Article
- Genome sequence of the novel freshwater Microcystis cyanophage Mwe-Yong1112-1.Archives of virology · 2022Article
- A Unique Set of Auxiliary Metabolic Genes Found in an Isolated Cyanophage Sheds New Light on Marine Phage-Host Interactions.Microbiology spectrum · 2022Article
- Article
- The Self-Bleaching Process of Microcystis aeruginosa is Delayed by a Symbiotic Bacterium Pseudomonas sp. MAE1-K and Promoted by Methionine Deficiency.Microbiology spectrum · 2022Article
- Comparative genomic analysis of five freshwater cyanophages and reference-guided metagenomic data mining.Microbiome · 2022Article
- A Review of Cyanophage-Host Relationships: Highlighting Cyanophages as a Potential Cyanobacteria Control Strategy.Toxins · 2022Review
10 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cyanobacteria and their phages are significant microbial components of the freshwater and marine environments. We identified a lytic phage, Ma-LMM01, infecting Microcystis aeruginosa, a cyanobacterium that forms toxic blooms on the surfaces of freshwater lakes. Here, we describe the first sequenced freshwater cyanomyovirus genome of Ma-LMM01. The linear, circularly permuted, and terminally redundant genome has 162,109 bp and contains 184 predicted protein-coding genes and two tRNA genes. The genome exhibits no colinearity with previously sequenced genomes of cyanomyoviruses or other Myoviridae. The majority of the predicted genes have no detectable homologues in the databases. These findings indicate that Ma-LMM01 is a member of a new lineage of the Myoviridae family. The genome lacks homologues for the photosynthetic genes that are prevalent in marine cyanophages. However, it has a homologue of nblA, which is essential for the degradation of the major cyanobacteria light-harvesting complex, the phycobilisomes. The genome codes for a site-specific recombinase and two prophage antirepressors, suggesting that it has the capacity to integrate into the host genome. Ma-LMM01 possesses six genes, including three coding for transposases, that are highly similar to homologues found in cyanobacteria, suggesting that recent gene transfers have occurred between Ma-LMM01 and its host. We propose that the Ma-LMM01 NblA homologue possibly reduces the absorption of excess light energy and confers benefits to the phage living in surface waters. This phage genome study suggests that light is central in the phage-cyanobacterium relationships where the viruses use diverse genetic strategies to control their host's photosynthesis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.